Results 221 to 230 of about 60,053,446 (390)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Vibration perception threshold assessments: Comparing the Staircase and von Békésy methods. [PDF]

Atten Percept Psychophys
Silva E, Costa N, Lisboa IC.
europepmc   +1 more source

Erosion and Hot Corrosion Phenomena in Thermal Power Plant and their Preventive Methods: A Study

, 2018
Rakesh Kumar, Ranjan Singh, Santosh Kumar   +2 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Phase Correction of MR Spectroscopic Imaging Data Using Model-Based Signal Estimation and Extrapolation. [PDF]

IEEE Trans Biomed Eng
Jin W, Guo R, Li Y, Zhao Y, Li X, Zhu XH, Chen W, Liang ZP.   +7 more
europepmc   +1 more source

Exploratory modeling and analysis: a promising method to deal with deep uncertainty

, 2008
B. Agusdinata
openalex   +1 more source

A new method for measuring daytime sleepiness: the Epworth sleepiness scale.

Sleep, 1991
M. Johns
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Treatment outcome of the Ponseti method for clubfoot in Africa : a systematic review and meta-analysis. [PDF]

Bone Jt Open
Abdu SM, Assefa EM, Tareke AA.
europepmc   +1 more source

Portraits of Plurilingualism in a French International School in Toronto: Exploring the Role of Visual Methods to Access Students’ Representations of their Linguistically Diverse Identities

, 2014
Gail Prasad
openalex   +1 more source