Results 141 to 150 of about 9,776,899 (294)

A mixed method comparison of stigma toward autism and schizophrenia and effects of person-first versus identity-first language. [PDF]

Front Psychiatry, 2023
Jones DR, Sasson NJ.
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Multiple linear regression modeling with values below a lower limit of quantification - a statistical method comparison. [PDF]

BMC Med Res Methodol
Hafermann L, Yokota I, Kalski L, Wolfarth B, Herrmann C.   +4 more
europepmc   +1 more source

Method comparison and estimation of causal effects of insomnia on health outcomes in a survey sampled population. [PDF]

Sci Rep, 2023
Shahu A, Chung J, Tarraf W, Ramos AR, González HM, Redline S, Cai J, Sofer T.   +7 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Cocoa pulp as a novel source of plant-derived exosome-like nanovesicles: method comparison and physicochemical characterization. [PDF]

Front Bioeng Biotechnol
Tapia-Aguayo A, Krüger S, Wessjohann LA, Chica MJ, Hinderberger D, Volmer J, González-Valdez J, Ramos-Parra PA, Fernández-Niño M.   +8 more
europepmc   +1 more source

Method Comparison and Clinical Performance of Breast Cancer Tumor Markers on Novel Multiplex Immunoassay and Automatized LOCI Technology Platforms. [PDF]

Diagnostics (Basel), 2023
Schröder L, Mallmann MR, Domroese CM, Wefers N, Dolscheid-Pommerich R, Stoffel-Wagner B, Trulson I, Vahldiek K, Klawonn F, Holdenrieder S.   +9 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Sample size estimation for local hypothesis testing of functional data in medical studies: method comparison, recommendations, and a web application. [PDF]

BMC Med Res Methodol
Seydi MR, Strandberg J, Pataky TC, Schelin L.   +3 more
europepmc   +1 more source

How low can we (reliably) go? A method comparison of thyroid-stimulating hormone assays with a focus on low concentrations. [PDF]

Eur Thyroid J, 2023
Ursem SR, Boelen A, Hillebrand JJ, den Elzen WPJ, Heijboer AC.   +4 more
europepmc   +1 more source