Results 231 to 240 of about 9,776,899 (294)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Model Comparison Methods

2004
Publisher Summary This chapter describes the various aspects of model comparison methods. The question of how one should choose among competing explanations of observed data is at the core of science. Model comparison is ubiquitous and arises, for example, when a toxicologist must decide between two dose-response models or when a biochemist needs to ...
Jay I, Myung, Mark A, Pitt
openaire   +2 more sources

Comparison of analytical methods

Meat Science, 1989
A technique for comparing two analytical methods is presented in this paper. Frequently a new method, generally simpler, faster or less expensive, is compared with a reference method. The deterministic relationships between two methods, subject only to random errors, is first discussed.
L, Körmendy, V, Mihályi, E, Zukál, A, Csiba   +3 more
openaire   +2 more sources

Modelling method comparison data

Statistical Methods in Medical Research, 1999
We explore a range of linear regression models that might be useful for either: (a) the relative calibration of two or more methods or (b) to evaluate their precisions relative to each other. Ideally, one should be able to use a single data set to carry out the jobs (a) and (b) together. Throughout this review we consider the constraints (assumptions)
Dunn, Graham, Roberts, Chris
openaire   +2 more sources

Efficiency comparison method

Proceedings of the 2012 IEEE International Symposium on Antennas and Propagation, 2012
A method to evaluate radiation efficiency is proposed. Normally the antenna gain is measured by comparing the gain of an antenna under test (AUT) with that of a standard gain horn (SGH). Once the gain is available, the antenna efficiency is computed assuming the directivity is available.
Bhavyang Ramesh Mehta, Choon Sae Lee, Mohamed Ezzat, Yong Zhu, George Chang   +4 more
openaire   +1 more source

Methods comparison.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2018
The current report discusses the process in which a methods comparison study in the National Animal Health Laboratory Network is performed. Specific details are provided for designing and analyzing studies intended to evaluate analytical sensitivity, efficiency, analytical specificity, cross-contamination, repeatability, operator variability, and to ...
Monica M, Reising, Kate R, Schumann, Beate M, Crossley, Patricia S, Glas, Richard H, Jacobson, Kathy L, Toohey-Kurth, Janice C, Pedersen, David, Siev, Barbara M, Martin   +8 more
openaire   +1 more source

Analysis of Method Comparison Studies

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1996
o-+------,r-----,----,.-------, intercept of zero and a slope of one. These requirements can even be formally tested if the standard errors of the slope and intercept are also supplied. It should be noted that statistical packages will usually give a significance test of the slope compared to zero rather than one.
openaire   +3 more sources

The Comparison Method

1977
The role of the comparison method, as already studied in Section II.3, might be roughly characterized as follows: the solutions of the comparison equation push on before themselves those of the original equation. Following V. M. Matrosov [1973], this can be viewed as an interesting extension of the notion of a mathematical model.
N. Rouche, P. Habets, M. Laloy
openaire   +1 more source