Results 271 to 280 of about 8,855,165 (345)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

A Novel Multiband Fusion Method Considering Scattering Characteristic Fluctuation Between Sub-Bands. [PDF]

Sensors (Basel)
Li P, Luo L, Huang D.
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Evaluation of the functional outcome measures of recurrent clubfeet after posteromedial or posterior release treated using the Ponseti method: a preliminary study : Title page. [PDF]

BMC Musculoskelet Disord
Ding J, Dai ZZ, Zhao L, Wu ZK.
europepmc   +1 more source

Information Indicators of Occurrence and Monitoring of Material Structure Degradation in Vibrodiagnostic Systems During Loading. [PDF]

Materials (Basel)
Sharko A, Stepanchikov D, Sharko O, Buketov A, Louda P, Maslyiak B, Kyrylovych V, Svyrydov V, Czarnywojtek P, Dębczyński M, Łoś P, Łoś KE.   +11 more
europepmc   +1 more source

Risky fertility characteristics and determinants of pastoralist women: the case of southeastern Anatolia region. [PDF]

BMC Womens Health
Gül S, Koruk F.
europepmc   +1 more source

Data-driven vehicle stability control via co-simulation of digital twin and constrained MPC. [PDF]

Sci Rep
Lin M, Zhang Z, Huang M, Ding Y.
europepmc   +1 more source

Estimation Of A Smooth And Convex Receiver Operator Characteristic Curve: A Comparison Of Parametric And Non-Parametric Methods

, 2016
Abdelrahman M. M. Zamzam
openalex   +1 more source

Adaptive Hoyer-L-Moment Envelope Spectrum: A Method for Robust Demodulation of Ship-Radiated Noise in Low-SNR Environments. [PDF]

Sensors (Basel)
Zhang R, Wang Q, Du S.
europepmc   +1 more source

Towards a minimum reporting standard to promote animal welfare and data quality in biologging research. [PDF]

Anim Biotelemetry
Payne AR, Hale CM, Davidson SC, Kendall-Bar JM, Beltran RS.   +4 more
europepmc   +1 more source