Results 111 to 120 of about 304,989 (278)

Detecting flying objects in synthetic aperture radar images using Moving Target Indicator methods

IET Radar, Sonar & Navigation
The growing proliferation of synthetic aperture radar (SAR) sensors brings the tantalising prospect of extending their utility into ‘novel’ applications.
Elliot J. Hansen, Brian W.‐H. Ng, Mark Preiss   +2 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Hopf's lemma, asymptotic radial symmetry, and monotonicity of solutions to the logarithmic Laplacian parabolic system

Advances in Nonlinear Analysis
In this article, we extend the asymptotic method of moving planes to the following logarithmic Laplacian parabolic system: ∂z∂t(η,t)+(−△)ℒz(η,t)=f(t,v(η,t)),(η,t)∈B1(0)×[0,∞),∂v∂t(η,t)+(−△)ℒv(η,t)=g(t,z(η,t)),(η,t)∈B1(0)×[0,∞),z(η,t)=0,v(η,t)=0,(η,t)∈B1c(
Wang Guotao, Wang Jing
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Variational and numerical aspects of a system of ODEs with concave-convex nonlinearities

Electronic Journal of Differential Equations
We study a Hamiltonian system of ordinary differential equations under Dirichlet boundary conditions. The system features a mixed (concave-convex) power nonlinearity with a positive parameter $\lambda$. We show multiplicity of nonnegative solutions for a
Oscar Agudelo, Gabriela Holubova, Martin Martin Kudlac   +2 more
doaj  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Solutions of elliptic equations with a level surface parallel to the boundary: stability of the radial configuration

, 2013
Positive solutions of homogeneous Dirichlet boundary value problems or initial-value problems for certain elliptic or parabolic equations must be radially symmetric and monotone in the radial direction if just one of their level surfaces is parallel to ...
Ciraolo, Giulio, Magnanini, Rolando, Sakaguchi, Shigeru   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source