Results 151 to 160 of about 166,841,558 (307)

Clinicians' practices and attitudes toward depression assessment: a cross-sectional survey study. [PDF]

BMC Psychol
Navandi D, Eijsbroek VC, Wiebel C, Marker A, Kjell K, Molendijk ML, Stade EC, Kjell ONE.   +7 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Letter: Jane Scales to Ida M. Tarbell, March 31, 1931

, 1931
Letter of five ...
Scales, Jane
core  

Spatial Collinearity Constrains Multivariate Molecular-Enriched Network Estimation. [PDF]

Hum Brain Mapp
Lawn T, Nakuci J, Williams SCR, Turkheimer F, Mehta MA.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Seeing Skin Tone Differently: An Experimental Comparison of Objective Measurements and Subjective Perceptions. [PDF]

Bioengineering (Basel)
Sooriyaarachchi J, Proulx C, Pecora L, Rivest-Hénault D, Vaughan T, Rainville MA, Saull A, Fortin A, Jiang D.   +8 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Comparison of methods in the analysis of dependent ordered catagorical data [PDF]

Rating scales for outcome variables produce categorical data which are often ordered and measurements from rating scales are not standardized. The purpose of this study is to apply commonly used and novel methods for paired ordered categorical data to ...
Högberg, Hans, Svensson, Elisabeth
core  

Weighted multi-scale and wavelet-enhanced Segment Anything Model for salient object detection. [PDF]

PLoS One
Liu Z, Tian D.
europepmc   +1 more source