To What Extent Can We Extrapolate Proteochemometric Models: A Case Study for the SLC6 Transporter Family. [PDF]
Abu-Shehab U, Ecker G.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Building a sustainable management pipeline: Key predictors of nurse management aspirations in Ireland. [PDF]
Berkery E, Ryan NF, Purtill H.
europepmc +1 more source
Application of Computer Algebra for the Method of Multiple Scales.
openaire +2 more sources
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
From free association to free parameters: machine-learning empowers artificial intelligence models to rate the affective-relational aspects of narratives like an expert psychologist. [PDF]
Siefert CJ +6 more
europepmc +1 more source
Multiple Scale Method for Nonlinear Wave Modulation
Kakutani, Tsunehiko, Kawahara, Takuji
openaire +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Research on multimodal dense small object detection algorithms guided by cross-modal information. [PDF]
Hu J +7 more
europepmc +1 more source
Abnormal head movements in neurological conditions: a knowledge-based dataset with application to cervical dystonia. [PDF]
Al-Dabet S, Turaev S, Zaki N.
europepmc +1 more source

