Results 51 to 60 of about 173,732,863 (238)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Comparison of emerging Chinese robot-assisted surgery systems and the da Vinci surgical system: A meta-analysis and systematic review

Asian Journal of Surgery
To synthesize and compare the intraoperative performance of the emerging Chinese surgical robot (CNR) and its postoperative impacts on patients with the Da Vinci surgical robot (DVR).
Zehao Yu, Jiawei Chen, Yarong Song, Qingliu He, Liang Chen, Kang Chen, Yifei Xing   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Accuracy of occurrence and abundance estimates from insect metabarcoding

Methods in Ecology and Evolution
DNA metabarcoding—high‐throughput sequencing of barcode regions from bulk samples—has become a key tool for insect biodiversity assessment. Yet, how methodological choices affect the accuracy of metabarcoding data remains insufficiently explored. In this
Ela Iwaszkiewicz‐Eggebrecht, Emma Granqvist, Karol H. Nowak, Catalina Valdivia, Mateusz Buczek, Amrita Srivathsan, Emily Hartop, Andreia Miraldo, Tomas Roslin, Ayco J. M. Tack, Piotr Łukasik, Rudolf Meier, Fredrik Ronquist   +12 more
doaj   +1 more source

Comparative performance of air sampling methods in a broiler house: implications for use and recovery of bacteria

Poultry Science
Accurate quantification of airborne bacteria in broiler houses is essential for assessing exposure risks to workers and animals, as well as for developing informed sanitation and surveillance strategies.
J.T. Porzeinski, L.A. Wythe, A.P. McElroy, M.B. Farnell   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A Missing Link: Nutritional Healing in Recovery [PDF]

, 2018
The journey of students in a Collegiate Recovery Program (CRP) begins with early recovery and continues towards a well-developed mental, spiritual, emotional, and physical state. Much emphasis is placed on mental, emotional, and spiritual healing through
Henley, Emmy L
core   +1 more source

Fruits and Seeds as Indicators of the Genetic Diversity of Hymenaea martiana (Fabaceae) in Northeast Brazil

Biology
Hymenaea martiana is a species native to Brazil. It has ecological value, contributes to forest restoration, and is economically important because of the use of its wood and fruits. However, it is frequently exploited.
Joyce Naiara da Silva, Guilherme Vinícius Gonçalves de Pádua, Caroline Marques Rodrigues, João Henrique Constantino Sales Silva, Cosma Layssa Santos Gomes, Marília Hortência Batista Silva Rodrigues, Maria Karoline Ferreira Bernardo, Eduardo Luã Fernandes da Silva, Luís Gustavo Alves de Almeida, Lenyneves Duarte Alvino de Araújo, Aline das Graças Souza, Naysa Flávia Ferreira do Nascimento, Edna Ursulino Alves   +12 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source