Results 101 to 110 of about 1,334,154 (310)
Photovoice and House Meetings Within Participatory Action Research [PDF]
, 2016 Participatory action research (PAR) is an epistemology where community members and researchers collaborate to (a) determine the problem to be researched, (b) collect data, (c) analyze data, (d) come to a conclusion, (e) determine an intervention, (f ...
Ferńandez, Jesica S. +3 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Discursive paradigm of research of a literary text
Записки з романо-германської філології, 2015 The article defines discursive status of a literary text and outlines the role of the text in the act of literary communication. It also shows the dynamics study of a literary text in linguistics in terms of different methodological approaches and ...
Н. В. Кондратенко
doaj +1 more source
Experience Sampling refers to the repeated sampling of momentary experiences in the individual’s natural environment. Methodological advantages include the minimization of retrospective response biases and the maximization of the validity of the ...
Michaela Riediger
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
, 2015 This paper describes the practice of systemic intervention, emphasizing (1) the need to explore stakeholder values and boundaries for analysis; (2) responses to the challenges of marginalization processes; and (3) a wide, pluralistic range of methods ...
Midgley, Gerald
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Warren J. Samuels (1933-2011) [PDF]
, 2012 This paper examines the research and career of the late Warren J. Samuels (1933-2011), an influential institutionalist economist in the Wisconsin John Commons tradition and well-known historian and methodologist of economics.
Davis, John B.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source