Results 131 to 140 of about 1,334,154 (310)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The methodological status of co-authorship networks
, 2008 A powerful strategy within the study of collaboration in science is to posit that co-authorship patterns represent social networks. It is prerequisite to an application of Social Network Analysis (SNA) to define the network entities. A network analysis of the inter-institutional collaboration in COLLNET on the basis of co-authorships was conducted. The
Jahn, Najko +2 more
openaire +3 more sources
Ethnic groups struggle for status: The role of religion [PDF]
Социологический журнал, 2012 This article is devoted to theoretical analysis of the mechanisms and factors of ethnic groups struggle for status and particularly instrumental role of religion as a cultural phenomenon.
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
HEART RATE VARIABILITY ASSESSMENT AND ITS POTENTIAL
Российский кардиологический журнал, 2011 Heart rate variability (HRV) is a new method of non-invasive assessment of functional status, various levels of regulatory systems, and adaptation to internal and external factors.
Buy Min Ziep, E. O. Taratukhin
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Measuring Subjective Wellbeing in Developing Countries. [PDF]
, 2004 The paper explores the conceptual and methodological issues entailed in using subjective measures of well-being in developing countries. In the first part I define, situate and contrast subjective quality of life (QoL), subjective well-being (SWB), and ...
Camfield, Laura
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Application progress of knowledge translation theory in clinical practice
Huli yanjiu, 2018 This article reviewed the definition,classification,theory frame,and the application status quo in the clinical practice of knowledge translation,aimed at encouraging nursing staff in China to translate evidence based knowledge into clinical practice,and
王慧 +4 more
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