Results 51 to 60 of about 1,334,154 (310)

Chomsky on methodological naturalism. On the scientific status of Chomsky’s research programs

Rivista Internazionale di Filosofia e Psicologia
Immediately after introducing transformational grammar in Syntactic structures, Noam Chomsky began to employ the formal grammar he developed to investigate language from an internalist and nativist perspective.
Enrico Cipriani
doaj   +1 more source

Impact of destruction – Introduction to the Josephus Seminar, Theological University Kampen

HTS Teologiese Studies/Theological Studies, 2015
This is an introduction to the contributions of Jan Willem van Henten and William den Hollander to the Josephus Seminar ‘Impact of destruction. Methodological questions in the study of Jewish and Christian reactions to the demolition of the Temple’ held ...
Koert van Bekkum
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Small-sided games: An umbrella review of systematic reviews and meta-analyses.

PLoS ONE, 2021
ObjectiveThis umbrella review was conducted to summarize the evidence and qualify the methodological quality of SR and SRMA published on small-sided games in team ball sports.MethodsA systematic review of Web of Science, PubMed, Cochrane Library, Scopus,
Filipe Manuel Clemente, José Afonso, Hugo Sarmento   +2 more
doaj   +1 more source

A century of methodological individualism part 1: Schumpeter and Menger [PDF]

, 2010
2009 marks the centenary of methodological individualism (MI). The phrase was first used in English in a 1909 QJE paper by Joseph Schumpeter. Yet after 100 years there is considerable confusion as to what the phrase means.
Denis, A.
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Methods for identifying health status from routinely collected health data: An overview

Integrative Medicine Research
The use of routinely collected health data (RCD) is currently helping to accelerate publications that evaluate the effectiveness and safety of medicines and medical devices.
Mei Liu, Ke Deng, Mingqi Wang, Qiao He, Jiayue Xu, Guowei Li, Kang Zou, Xin Sun, Wen Wang   +8 more
doaj   +1 more source

Methodological status of time in political science

Moscow State University Bulletin. Series 18. Sociology and Political Science, 2020
In contemporary political science time is becoming a portmanteau-concept. It forms terminological concatenations in all fields of theoretical and applied researches. At the same time methodological status of time in political science is still not clear. Author suggests a systematization of those researches there time is viewed as a meaningful factor in
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source