Results 81 to 90 of about 870,794 (213)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Therapeutic scarification, shadow pain, and integrative geriatric rehabilitation for chronic musculoskeletal pain in older adults in Cameroon: a prospective mixed-methods observational study. [PDF]

Front Pain Res (Lausanne)
Npochinto Moumeni I, Njikam Moumeni AN, Alima JM, Mourey F, Atemkeng Tsatedem F.   +4 more
europepmc   +1 more source

Provider perceptions of the anticipated benefits, barriers, and facilitators associated with implementing a stepped care model for the delivery of addiction and mental health services in New Brunswick: a mixed-methods observational implementation study. [PDF]

Int J Ment Health Syst, 2023
King A, Harris-Lane LM, Bérubé S, Burke K, Churchill A, Cornish P, Goguen B, Jaouich A, Rash JA.   +8 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

UnderstandingDelirium.ca: A Mixed-Methods Observational Evaluation of an Internet-Based Educational Intervention for the Public and Care Partners. [PDF]

Geriatrics (Basel)
Shen R, Hadid D, Ayers S, Clark S, Woodburn R, Grad R, Levinson AJ.   +6 more
europepmc   +1 more source

Evaluation of a virtual coaching system eHealth intervention: A mixed methods observational cohort study in the Netherlands. [PDF]

Internet Interv, 2022
Hurmuz MZM, Jansen-Kosterink SM, Beinema T, Fischer K, Op den Akker H, Hermens HJ.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Response to letters to the editor on 'Reducing plastic in single-use central line insertion packs: a mixed methods observational study'. [PDF]

Anaesth Intensive Care
Seville AR, Kazda L, McAlister S, Bell KJ.   +3 more
europepmc   +1 more source

Contextually appropriate communication strategies for COVID-19 prevention in Kenya border regions: evidence from a mixed methods observational study in Busia and Mandera counties. [PDF]

BMJ Open, 2023
Kaduka L, Olale J, Karamanos A, Mutai J, Coultas C, Ahmed I, L'Esperance V, Read U, Dazzan P, Cruickshank JK, Muniu E, Harding S.   +11 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source