Results 81 to 90 of about 793,803 (212)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Reducing plastic in single-use central line insertion packs: A mixed methods observational study. [PDF]

open access: yesAnaesth Intensive Care
Seville AR   +5 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Biological Mechanisms in Pregnant Women With Anxiety (Happy Mother-Healthy Baby Supplement Study): Protocol for a Longitudinal Mixed Methods Observational Study.

open access: yesJMIR Res Protoc, 2023
Sherer ML   +10 more
europepmc   +1 more source

Hand hygiene during facility-based childbirth in Cambodia: a theory-driven, mixed-methods observational study. [PDF]

open access: yesBMC Pregnancy Childbirth, 2021
Nalule Y   +7 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The observational method

open access: yes, 2010
One project is studying how the value of a preinvestigation shall be estimated by comparing the cost of the investigations with the utility of the received information. It will give the very base for a descision if the Observational Method should be applied or the design should be based on calculations or emperical based knowledge.
Stille, Håkan   +3 more
openaire   +1 more source

A Mixed Methods, Observational Investigation of Physical Activity, Exercise, and Diet Among Older Ugandans Living With and Without Chronic HIV Infection. [PDF]

open access: yesJ Assoc Nurses AIDS Care, 2021
Wright CH   +7 more
europepmc   +1 more source

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