Results 111 to 120 of about 63,025,606 (387)

New Method for the Synthesis of 2D Vanadium Nitride (MXene) and Its Application as a Supercapacitor Electrode [PDF]

open access: gold, 2020
Sandhya Venkateshalu   +8 more
openalex   +1 more source

Bayesian computational methods

open access: yes, 2010
In this chapter, we will first present the most standard computational challenges met in Bayesian Statistics, focussing primarily on mixture estimation and on model choice issues, and then relate these problems with computational solutions.
Robert, Christian P.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Learning on the job: using Artificial Intelligence to support rapid review methods

open access: yesJournal of the Medical Library Association
The National Collaborating Centre for Methods and Tools’ (NCCMT) Rapid Evidence Service conducts rapid reviews on priority questions to respond to the needs of public health decision-makers.
Kristin Rogers   +3 more
doaj   +1 more source

Immigrants and electoral enrolment: Do the numbers add up? [PDF]

open access: yes
: The electoral enrolment of immigrants is important for effective democracy. Electoral rolls also provide useful administrative data on the age, regional distribution, and intercensal movements of the eligible voting population.
Anne Henderson
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Alcohol consumption as a socially contagious phenomenon in the Framingham Heart Study social network

open access: yesScientific Reports
We use longitudinal social network data from the Framingham Heart Study to examine the extent to which alcohol consumption is influenced by the network structure.
Maarten W. J. van den Ende   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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