Results 261 to 270 of about 63,025,606 (387)

Benchmarking interpretability of deep learning for predictive genomics: Recall, precision, and variability of feature attribution. [PDF]

PLoS Comput Biol
Reynolds J, Pan C.
europepmc   +1 more source

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source

Effectiveness of Cleaning Methods for Resilient Denture Liners: A Three-Period Randomized Crossover Trial. [PDF]

Clin Exp Dent Res
Takeuchi R, Miyamae S, Sonobe N, Hattori H, Morinaga Y, Hotta H, Hasegawa Y, Kimoto S.   +7 more
europepmc   +1 more source

Every ROSE has its thorns

Environmental Evidence, 2018
Melissa K. Sharp, Linda Nyanchoka, Darko Hren   +2 more
doaj   +1 more source

The importance of methods and methods in nanotechnology, chemical science and industry [PDF]

, 2018
Kosmina, Natalya, Krichkovskaya, Lidiya, Petrov, Sergey   +2 more
core  

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

The value of AI-assisted multiple bone age assessment methods for evaluating efficacy in idiopathic short stature: A retrospective study of traditional Chinese medicine treatment for girls in China. [PDF]

Medicine (Baltimore)
Wang W, Yu R, Hu Y, Le D, Shen P, Wang Z.   +5 more
europepmc   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

A cost-utility analysis for return-to-work interventions comparing alternative methods for handling missing health-related quality of life data. [PDF]

J Rehabil Med
Nguyen C, Burger EA, Aasdahl L, Morgante N, Fimland MS, Bjørnelv GMW.   +5 more
europepmc   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source