Results 41 to 50 of about 8,131,923 (301)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Testing methods and techniques - A compilation [PDF]

Nondestructive test methods and techniques including computer programs and data ...

core   +4 more sources

Towards FAIR Data Management in Heritage Science Research: Updates and Progress on the INFRA-ART Spectral Library

Heritage
The heritage science sector is facing a critical need for accessible and comprehensive data resources to facilitate research, preservation efforts, and interdisciplinary collaboration. The concept of FAIR data management involves embracing principles and
Ioana Maria Cortea
doaj   +1 more source

Minimax Approach for Semivariogram Fitting in Ordinary Kriging

IEEE Access, 2020
This research paper aims to analyze the minimax approach used in the semivariogram fitting process that forms one stage of the kriging operation performed for interpolation.
Andie Setiyoko, T. Basaruddin, Aniati Murni Arymurthy   +2 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Acceleration techniques for regularized Newton methods applied to electromagnetic inverse medium scattering problems

, 2010
We study the construction and updating of spectral preconditioners for regularized Newton methods and their application to electromagnetic inverse medium scattering problems.
Hohage, Thorsten, Langer, Stefan
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Applying vision transformers to the spectral analysis of astronomical objects

Astronomy & Astrophysics
We applied pretrained vision transformers (ViTs), originally developed for image recognition, to the analysis of astronomical spectral data. By converting traditional 1D spectra into 2D image representations, we enable ViTs to capture both local and ...
Strano Moraes Luis Felipe, Becker Ignacio, Protopapas Pavlos, Cabrera-Vives Guillermo   +3 more
doaj   +1 more source

Characterization of Streptococcus pneumoniae strains causing invasive infections using whole-genome sequencing

Журнал микробиологии, эпидемиологии и иммунобиологии, 2020
Purpose: antigenic and genetic characterization of Streptococcus pneumoniae strains isolated from patients with invasive forms of pneumococcal infection using whole-genome sequencing.Materials and Methods. The study was performed on 46 S.
Konstantin O. Mironov, Vitaly I. Korchagin, Yuliya V. Mikhailova, Yurii G. Yanushevich, Andrey A. Shelenkov, Aida N. Chagaryan, Natali V. Ivanchik, Roman S. Kozlov, Vasily G. Akimkin   +8 more
doaj   +1 more source