Results 101 to 110 of about 3,768,575 (328)

Researching Online Foreign Language Interaction and Exchange: Theories, Methods and Challenges

open access: yesWorking Papers in Applied Linguistics and TESOL, 2015
Telecollaboration refers to the use of online communication tools to connect language learners in different countries in collaborative projects and intercultural exchange (Belz, 2001).
Farah S. Akbar
doaj   +1 more source

Cost-of-illness studies: concepts, scopes, and methods

open access: yesClinical and Molecular Hepatology, 2014
Liver diseases are one of the main causes of death, and their ever-increasing prevalence is threatening to cause significant damage both to individuals and society as a whole.
C. Jo
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Researching Online Foreign Language Interaction and Exchange: Theories, Methods and Challenges

open access: yesStudies in Applied Linguistics & TESOL, 2013
Telecollaboration refers to the use of online communication tools to connect language learners in different countries in collaborative projects and intercultural exchange (Belz, 2001).
Farah S. Akbar
doaj   +1 more source

Overview of Learning Theories (Chapter 1 of Faith-Based Education that Constructs)

open access: yes, 2010
Virtually everyone would agree that the role of the school is to help students learn. The school, as an institution of education, must incorporate a sense of morality or values.
Espinor, Debra S.
core  

Probing the physical and mathematical structure of $f(R)$ gravity by PSR $J0348+0432$

open access: yes, 2014
There are several approaches to extend General Relativity in order to explain the phenomena related to the Dark Matter and Dark Energy. These theories, generally called Extended Theories of Gravity, can be tested using observations coming from ...
De Laurentis, Mariafelicia   +1 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Theories and Methods for Labeling Cognitive Workload: Classification and Transfer Learning

open access: yesFrontiers in Human Neuroscience, 2019
There are a number of key data-centric questions that must be answered when developing classifiers for operator functional states. “Should a supervised or unsupervised learning approach be used?
Ryan McKendrick   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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