Results 21 to 30 of about 4,406 (220)
, 2010 Archaeological excavations in the sites of the Indus Valley civilization (2500-1900 BCE) in Pakistan and northwestern India have unearthed a large number of artifacts with inscriptions made up of hundreds of distinct signs.
Ashraf Md Izhar +32 more
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
RUDN Journal of Language Studies, Semiotics and SemanticsDue to its heterogeneous nature, a translingual literary text causes certain difficulties for research. Being created by the author in a language that is not ethnically primary for him, it contains both exophonic elements marking its foreign cultural ...
Karlygash E. Nurmaganbet +3 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Journal of Criminal Law, Criminology, and Police Science, 1953 Donald Doud is an Examiner of Questioned Documents who is associated with John F. Tyrrell in Milwaukee, Wisconsin. He has been a lecturer on various training programs for investigators, prosecutors, and attorneys at universities in the mid west, and his present paper is based upon his lecture given at the 7th Annual Arson Investigators Training Course ...
openaire +2 more sources
, 2015 A classic tension exists between exact inference in a simple model and approximate inference in a complex model. The latter offers expressivity and thus accuracy, but the former provides coverage of the space, an important property for confidence ...
Liang, Percy, Steinhardt, Jacob
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Recognizing Degraded Handwritten Characters [PDF]
, 2011 In this paper, Slavonic manuscripts from the 11th century written in Glagolitic script are investigated. State-of-the-art optical character recognition methods produce poor results for degraded handwritten document images.
Diem, Markus +3 more
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The rediscovery of Palmyra and its dissemination in Philosophical Transactions [PDF]
, 2016 This paper examines the first publicly documented western encounter with the ancient city of Palmyra as an archaeological site. This encounter was achieved in the late seventeenth century by a group of British merchants, who reached Palmyra and made ...
Astengo, G
core +1 more source