Results 41 to 50 of about 10,204 (154)

Evaluation of a learner-designed course for teaching health research skills in Ghana

BMC Medical Education, 2007
Background In developing countries the ability to conduct locally-relevant health research and high quality education are key tools in the fight against poverty.
Agbenyega Tsiri, Bedu-Addo George, Ansong Daniel, Bates Imelda, Akoto Alex, Nsiah-Asare Anthony, Karikari Patrick   +6 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Human Development in Russia: Major Achievements and Threats

Регионология, 2019
Introduction. A socially oriented state should strive to provide conditions for the harmonious development of its citizens. The solution of this task is often associated with a number of difficulties and threats, and therefore requires a detailed ...
Lyudmila N. Lipatova, Valentina N. Gradusova   +1 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Unia Europejska wobec wykluczenia społecznego – przykład interwencji przy udziale Europejskiego Funduszu Społecznego

Fides et Ratio, 2018
From the outset, the European Union's policy has focused on the dynamic development and social integration of its Member States, and the problem of poverty and social exclusion has been on the agenda since the 1970s.
Irena Drozd
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The Problem of Poverty Development in Russia and Methods to Fight Against It [PDF]

Prospects for Socio-Economic Development of Russia, 2020
Ekaterina Aleksandrovna Kurasova, Aleksandra Konstantinovna Maslennikova   +1 more
openaire   +1 more source

The Role of Social Work in Empowering People Living with HIV (PLHIV) for Poverty Alleviation in the Huye District in Rwanda

Journal of Comparative Social Work
People in need (PIN), such as people living with HIV/AIDS (PLHIV), are often discriminated against, isolated and disempowered. Consequently, it is not always easy for them to fight for their survival.
Charles Kalinganire
doaj   +1 more source