Results 51 to 60 of about 286,599 (266)

Human Development in Russia: Major Achievements and Threats

open access: yesРегионология, 2019
Introduction. A socially oriented state should strive to provide conditions for the harmonious development of its citizens. The solution of this task is often associated with a number of difficulties and threats, and therefore requires a detailed ...
Lyudmila N. Lipatova   +1 more
doaj   +1 more source

A Decade of Helping Civil Society Fight Corruption in the Philippines: Results and Lessons [PDF]

open access: yes, 2015
This Report details the results and lessons of a decade long (2003-2013) Partnership for Transparency Fund (www.ptfund.org) support to Filipino civil society organizations to fight corruption.
Jeffery Gutman, Vinay Bhargava
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Unia Europejska wobec wykluczenia społecznego – przykład interwencji przy udziale Europejskiego Funduszu Społecznego

open access: yesFides et Ratio, 2018
From the outset, the European Union's policy has focused on the dynamic development and social integration of its Member States, and the problem of poverty and social exclusion has been on the agenda since the 1970s.
Irena Drozd
doaj  

Women\u27s Resistance to Apartheid [PDF]

open access: yes, 2013
In lieu of an abstract, below is the essay\u27s first paragraph.Apartheid was an oppressively destructive system that influenced many lives, not only in South Africa, but also in many nearby provinces and countries.
Laber, Melinda
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Millenium Development Goals/UN and Sustainable Development Goals/UN as Instruments for Realising Sustainable Development Concept in the Global Economy [PDF]

open access: yes, 2017
This article presents the results of analysis and evaluation of the main effects of the implementation of the eight UN Millennium Development Goals, in force until 2015, and to demonstrate differences between and prospects for implementation of the new ...
Wysokińska, Zofia
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The Role of Social Work in Empowering People Living with HIV (PLHIV) for Poverty Alleviation in the Huye District in Rwanda

open access: yesJournal of Comparative Social Work
People in need (PIN), such as people living with HIV/AIDS (PLHIV), are often discriminated against, isolated and disempowered. Consequently, it is not always easy for them to fight for their survival.
Charles Kalinganire
doaj   +1 more source

Smoking inequality and health expenditures: a case study of Namibia

open access: yesTobacco Induced Diseases, 2018
Background Many parts of the world, specifically Low and Middle Income Countries (LMICs), have experienced increased smoking prevalence. This portends higher future smoking-related disease prevalence.
Zunda Chisha, John Ataguba
doaj   +1 more source

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