Results 51 to 60 of about 1,190 (187)

CSAKD: Determining Absolute Ligand Affinities From 19F NMR Chemical Shift Anisotropy

open access: yesAngewandte Chemie, EarlyView.
Affinity determination is crucial in drug discovery, yet remains difficult for weakly binding fragments. We introduce chemical shift anisotropy KD$K_{\text{D}}$ (CSAKD) by 19F$^{19}{\rm F}$ NMR relaxation experiments, a titration‐free method that requires no isotopic labeling.
Simon H. Rüdisser   +2 more
wiley   +2 more sources

Characteristics, Management, and Utilization of Muscles in Musculoskeletal Humanoids: Empirical Study on Kengoro and Musashi

open access: yesAdvanced Intelligent Systems, EarlyView.
Musculoskeletal humanoids exhibit rich biomechanical properties that remain insufficiently unified in prior discussions. This article systematically categorizes muscle characteristics into five properties: redundancy, independency, anisotropy, variable moment arm, and nonlinear elasticity, and analyzes their combined effects on control.
Kento Kawaharazuka   +2 more
wiley   +1 more source

Color‐Pure Organic Luminophores: Characteristics, Definitions, Physical Basis and Fundamental Design Principles

open access: yesAngewandte Chemie, EarlyView.
Color‐pure all‐organic emitters, i.e., with narrow spectral characteristics, are intensively studied for high‐definition organic LEDs and multi‐color bioimaging. In order to guide targeted materials design, this educative review discusses spectral characteristics, proper definitions and units, and the physical basis of spectral broadening, to distill ...
Johannes Gierschner   +6 more
wiley   +2 more sources

Adaptive Autonomy in Microrobot Motion Control via Deep Reinforcement Learning and Path Planning Synergy

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a data‐driven framework that combines deep reinforcement learning with classical path planning to achieve adaptive microrobot navigation. By training a surrogate neural network to emulate microrobot dynamics, the approach improves learning efficiency, reduces training time, and enables robust real‐time obstacle avoidance in ...
Amar Salehi   +3 more
wiley   +1 more source

Towards Advanced Intelligent and Perceptive Soft Grippers

open access: yesAdvanced Intelligent Systems, EarlyView.
Implementing soft yet strong and intelligent soft grippers request innovative and creative solutions in designing soft bodies and seamlessly integrating actuated systems with hierarchical sensing. This review systematically analyses soft grippers with a deep understanding of core components, from fundamental design principles to actuation and sensing ...
Haneul Kim   +4 more
wiley   +1 more source

Pre‐Curved Everting Robots With Embedded Steering Intelligence Fabricated by CO2 Laser Welding

open access: yesAdvanced Intelligent Systems, EarlyView.
Design and experimental demonstration of a laser welded growing robot for anatomically guided navigation. The robot follows an aortic arch phantom entering the branchiocephalic branch through steering by design. The figure shows the physical phantom setup, CAD defined weld geometry and full robot eversion.
Brandon Saldarriaga   +5 more
wiley   +1 more source

Profiling Co‐Occurrent Morphological Phenotypes and Their Degree of Expression Severity in Vacuolated Cells by Holo‐Tomographic Flow Cytometry and Fractal Analysis

open access: yesAdvanced Intelligent Systems, EarlyView.
HTFC gets 3D refractive index tomograms of flowing cells. Label‐free monocytes are engineered to express patterns of cytoplasmic vacuoles. From the tomogram, an efficient dimensionality reduction is operated. Interpretable features are extracted to classify the expression severity of phenotypes coexisting in each cell, visually represented by a seven ...
Marika Valentino   +9 more
wiley   +1 more source

Lost in aggregation? On the importance of local food price data for food poverty estimates

open access: yesAmerican Journal of Agricultural Economics, EarlyView.
Abstract This paper explores within‐country variations in food price dynamics and food poverty estimates by employing local market price data and national consumer price index (CPI) data. Our results show that national CPI data may be useful for approximating national trends but they fail to detect and identify spatial variations in local trends, which
Stephan Dietrich   +4 more
wiley   +1 more source

A new approach to calculate and forecast dynamic conditional correlation - the use of a multivariate heteroskedastic mixture model

open access: yes
Much research in finance has been directed towards forecasting time varying volatility of unidimensional macroeconomic variables such as stock index, exchange rate and interest rate.
Lu, Cheng
core  

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