Results 81 to 90 of about 793 (162)
Non-apoptotic cell death associated with perturbations of macropinocytosis
Frontiers in Physiology, 2015 Although macropinocytosis is widely recognized as a distinct form of fluid-phase endocytosis in antigen-presenting dendritic cells, it also occurs constitutively in many other normal and transformed cell types.
William A. Maltese, Jean H. Overmeyer
doaj +1 more source
Toxicity of Titanate Nanosheets on Human Immune Cells [PDF]
, 2017 Titanium oxide is regarded as a bio-inert material, but studies concerning the toxic effects of titanium dioxide (TiO2), particularly nano-scaled TiO2 particles, have been accumulating that indicate nano-scaled TiO2 particles show more harm and cause ...
Kumagai-Takei, Naoko +6 more
core +2 more sources
Crystal structure of (E)-3-(3-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-1-phenyl-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one, C27H21N5O [PDF]
, 2020 C27H21N5O, triclinic, P1̄ (no. 2), a = 8.1464(7) Å, b = 10.3861(8) Å, c = 13.2507(9) Å, α = 84.898(6)°, β = 89.413(6)°, γ = 80.351(7)°, V = 1100.88(15) Å3, Z = 2, Rgt(F) = 0.0648, wRref(F2) = 0.1726, T = 296(2 ...
Abdel-Wahab, Bakr F. +5 more
core +2 more sources
Structural activity and mechanistic studies on glycosylated antitumor ether lipids (GAELs) [PDF]
, 2015 A major impediment to successful treatment of cancer is the inability of clinically available drugs to kill cancer stems cells (CSCs), a subset of tumor cells that mediate progression, resistance and relapse of cancer. Glycosylated Antitumor Ether Lipids
Ogunsina, Makanjuola Ojo
core +2 more sources
Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.ABSTRACT Osteosarcoma, the most common primary malignant bone tumour, presents significant treatment challenges due to its complex tumour microenvironment and the development of chemoresistance. This study employs single‐cell transcriptomics to investigate chemotherapy‐induced changes in osteosarcoma at both the cellular and molecular levels.
Tao Jin +5 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.Western blotting was performed to analyze the expression of Caspase 3 and Cleaved‐Caspase 3 in Huh1 cells following different treatments, which supports the finding that bis‐heterocyclic chalcones 3d and 3f can inhibit the activity of hepatocellular carcinoma cells by inducing apoptosis.
Zhifen Li +4 more
wiley +1 more source
ACS Medicinal Chemistry Letters, 2013 Because many cancers harbor mutations that confer resistance to apoptosis, there is a need for therapeutic agents that can trigger alternative forms of cell death. Methuosis is a novel form of non-apoptotic cell death characterized by accumulation of vacuoles derived from macropinosomes and endosomes.
Christopher J, Trabbic +7 more
openaire +3 more sources
International Journal of Genomics, Volume 2026, Issue 1, 2026.Introduction Anoikis, a type of programmed cell death induced by detachment from the extracellular matrix (ECM), is crucial in cancer progression. Resistance to anoikis often correlates with enhanced invasion, metastasis, treatment resistance, and tumor recurrence.
Shan Li +5 more
wiley +1 more source
Identification of compounds that target glioma initiating cells [PDF]
, 2015 Glioblastoma multiforme is a common form of brain tumor that leads to debilitating effects despite the current regiment of treatment, which includes surgery, chemotherapy and radiotherapy.
Wee, Shimei
core +1 more source