Results 221 to 230 of about 53,659 (312)

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Inhibition and Rescue of Hyperglycemia‐Induced Cellular Senescence by Mitochondrial Transfer from Enucleated Mesenchymal Stem Cell‐Derived Microvesicles for Chronic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong   +3 more
wiley   +1 more source

Reconstructing Three‐Dimensional Optical Anisotropy with Tomographic Müller‐Polarimetric Microscopy

open access: yesAdvanced Science, EarlyView.
Tomographic Müller polarimetric microscopy is a novel imaging technique that resolves 3D birefringent properties of bulky samples, unveiling hierarchical nanostructures at microscopic resolution. Based on incoherent visible‐light polarimetry, it achieves experimental simplicity by eliminating phase measurements.
Yang Chen   +4 more
wiley   +1 more source

Stable Pincer Gold(III)‐TADF Emitters with Extended Donor–Acceptor Separation for Efficient Vacuum‐Deposited OLEDs with Operational Lifetime (LT95) up to 3831 h at 1000 cd m−2

open access: yesAdvanced Science, EarlyView.
Novel pincer gold(III)‐TADF (thermally activated delayed fluorescence) emitters with extended π‐distances exhibit small singlet‐triplet energy gaps (ΔEST), efficient reverse intersystem crossing (RISC), enhanced radiative decay rates and improved excitons utilization, leading to efficient electroluminescence.
Hui‐Xing Shu   +4 more
wiley   +1 more source

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