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Myocarditis and Methyldopa

Acta Medica Scandinavica, 1982
ABSTRACT. Six patients with myocarditis and hepatitis, attributed to an allergic reaction to methyldopa, are described. Granulomatous pneumonitis was also found in four of them.
J. G. M. Jordans   +2 more
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Methyldopa Poisoning

Journal of Toxicology: Clinical Toxicology, 1982
A case of methyldopa overdose, confirmed by quantitative blood analysis, is presented. The clinical manifestations were coma, hypothermia, hypotension, bradycardia, and dry mouth. This combination of clinical findings, previously considered characteristic of phenothiazines or tricyclic antidepressants poisoning, should also raise the suspicion of ...
Y, Shnaps   +3 more
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Methyldopa-induced pancreatitis

The American Journal of Digestive Diseases, 1978
An acute febrile illness associated with gastrointestinal upset developed in a patient within one week after starting treatment with methyldopa. The illness was characterized by prompt subsidence of symptoms when the patient withdrew therapy secondary to gastrointestinal upset, and recrudescence of symptoms when methyldopa therapy was reinitiated. This
Jorge G. Gutierrez   +3 more
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The Renal Excretion of Methyldopa

Scandinavian Journal of Clinical and Laboratory Investigation, 1972
The renal excretion of unconjugated methyldopa was studied in 17 patients on long-term therapy and in 7 patients following intravenous injection of 200 mg of the drug. The renal clearance of the conjugated drug was also determined in 9 cases. The renal function of the patients ranged from normal to severely impaired; even a patient with total anuria ...
Brodwall Ek   +3 more
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Hypertensive Responses to Methyldopa

New England Journal of Medicine, 1966
SEVERAL of the drugs currently employed in the management of arterial hypertension interfere with either the binding or the catabolism of norepinephrine in tissues. Administration of these drugs occasionally results in dangerous paradoxical pressor reactions.
Barry S. Strauch, Robert J. Levine
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