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Methylchloroisothiazolinone/Methylisothiazolinone and Methylisothiazolinone Allergies Can Be Detected by 200 ppm of Methylchloroisothiazolinone/Methylisothiazolinone Patch Test Concentration

Dermatitis, 2014
Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and methylisothiazolinone (MI) contact allergies are rising dramatically. Moreover, 100 ppm of MCI/MI patch test might not detect an important number of MCI/MI and MI allergies.This study aimed to present the prevalence of contact allergy to both preservatives in an area of Spain and to ...
Maria, Leiva-Salinas   +4 more
openaire   +2 more sources

Sensitization to Methylisothiazolinone in a group of Methylchloroisothiazolinone/Methylisothiazolinone allergic Patients

Cutaneous and Ocular Toxicology, 2012
In the EU, Methylisothiazolinone (MI) was approved as a preservative in cosmetics and household products in 2005. Since then, several cases of MI contact allergy have been reported. We studied the prevalence of MI sensitization in patients allergic to Methylchloroisothiazolinone/Methylisothiazolinone (MCI/MI).
Vasco Coelho, Macias   +4 more
openaire   +2 more sources

Methylisothiazolinone contact allergy – a growing epidemic

Contact Dermatitis, 2013
SummaryBackgroundThe prevalence of contact allergy to the isothiazolinone preservative methylchloroisothiazolinone (MCI) in combination with methylisothiazolinone (MI) and MI alone has increased in the last couple of years.ObjectivesTo investigate the prevalence of contact allergy to MI, MCI/MI and benzisothiazolinone (BIT) among patch tested patients ...
Lundov, Michael D   +2 more
openaire   +3 more sources

Methylisothiazolinone contact allergy: a review.

The British journal of dermatology, 2011
In the early 2000s the preservative methylisothiazolinone (MI) was released as an individual preservative for industrial products and, in 2005, it was permitted for use in cosmetic products. Up until then MI had been used only in combination with methylchloroisothiazolinone (MCI).
Lundov, M D   +3 more
openaire   +5 more sources

Methylisothiazolinone outbreak in the European Union

Current Opinion in Allergy & Clinical Immunology, 2015
The aim of this review was to examine the current outbreak of cases of contact allergy to methylisothiazolinone in Europe, a phenomenon that has also been observed worldwide, despite initial legislative control of the introduction of methylisothiazolinone into the market.Reported allergic contact reactions are primarily eczematous, most commonly in ...
Faheem, Latheef, Stephen Mark, Wilkinson
openaire   +2 more sources

T lymphocyte dynamics in methylisothiazolinone‐allergic patients

Contact Dermatitis, 2016
SummaryBackgroundMethylisothiazolinone (MI), a preservative that is commonly used in personal care products, is now recognized as an important contact allergen in both cosmetic and occupational settings.ObjectivesTo analyse T lymphocyte responses to MI, in order to provide important information regarding the relationship between the nature of such ...
Popple, Amy   +5 more
openaire   +2 more sources

Methylchloroisothiazolinone/Methylisothiazolinone and methylisothiazolinone allergy.

Dermatitis : contact, atopic, occupational, drug, 2015
Preservatives used in cosmetics tend to be, by their nature, allergenic. Methylisothiazolinone (MI) has been used as a sole preservative in multiple cosmetics, household goods, and toiletries. A current epidemic of MI has recently been reported in Europe.The aim of this study was to study the prevalence of methylchloroisothiazolinone/MI (MCI/MI) and MI
Pailin, Puangpet   +2 more
openaire   +1 more source

Further evidence of the methylisothiazolinone epidemic

Contact Dermatitis, 2014
Methylisothiazolinone (MI) appears to be causing a current epidemic of allergic contact dermatitis in Europe (1–4). We report patch test data of patients patch tested with MI from 2011 to 2013, including methylchloroisothiazolinone (MCI)/MI, at the Department of Dermatovenerology, Odense University Hospital.
Madsen, Jakob Torp   +1 more
openaire   +3 more sources

Methylchloroisothiazolinone/methylisothiazolinone and methylisothiazolinone contact allergy: A 24‐year, single‐center, retrospective cohort study from Turkey

Contact Dermatitis, 2020
AbstractBackgroundMethylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI allergy caused a global epidemic during the period 2010 to 2015, reaching its peak in 2013/14.ObjectiveTo investigate the characteristics of MCI/MI and MI allergy in Turkey over 24 years.MethodsA total of 2310 patients patch tested between 1996 and 2019 with MCI/MI 0.01%
Esen Özkaya   +3 more
openaire   +2 more sources

Multicenter Patch Testing With Methylisothiazolinone and Methylchloroisothiazolinone/Methylisothiazolinone Within the International Contact Dermatitis Research Group

Dermatitis, 2017
The preservatives methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI are well-known contact sensitizers. Recently, an increase in the contact allergy frequency for MI 0.2% aqueous (aq) has been seen in many European countries paralleled with an increase in MCI/MI allergy. Many of the MI-allergic patients do not react to MCI/MI 0.01% or 0.
Isaksson, Marléne   +9 more
openaire   +3 more sources

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