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Methylisothiazolinone contact allergy and dose-response relationships
Contact Dermatitis, 2011Methylisothiazolinone (MI) used alone is a new preservative causing a high prevalence of contact allergy. The eliciting threshold of MI is unknown. The combination of MI and phenoxyethanol enhances the antimicrobial efficacy of MI.The eliciting doses of MI contact allergy in a patch test and a repeated open application test (ROAT) were investigated. In
Lundov, Michael D +2 more
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Methylisothiazolinone and isothiazolinone allergy.
Cutis, 2020Methylisothiazolinone (MI) is a preservative commonly used in water-based personal care products. Increases in the allowable concentration of MI alone in these products has led to an epidemic of allergic contact dermatitis (ACD). Although personal care products are the most common source of MI contact allergy, other novel exposures include household ...
Margo, Reeder, Amber Reck, Atwater
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Prevalence and cause of methylisothiazolinone contact allergy
Contact Dermatitis, 2010Background: Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) has been one of the most frequent sensitizers since the 1980s. In 2005, the use of MI alone was approved for the preservation of cosmetic and household products in the EU. Before that, MI was used in industrial products, and the first cases of isolated MI contact allergy were ...
Lundov, Michael D +3 more
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Nederlands tijdschrift voor dermatologie en venereologie, 2017
Methylisothiazolinone (MI), a preservative used in cosmetics and industrial products, has been responsible for an 'epidemic' of contact allergy and allergic contact dermatitis in the past 7 years. In this article we discuss what MI is, in which products it can be found, the frequency of contact allergy to MI, what allergic contact dermatitis to MI ...
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Methylisothiazolinone (MI), a preservative used in cosmetics and industrial products, has been responsible for an 'epidemic' of contact allergy and allergic contact dermatitis in the past 7 years. In this article we discuss what MI is, in which products it can be found, the frequency of contact allergy to MI, what allergic contact dermatitis to MI ...
openaire +1 more source
Contact dermatitis, 2017
Contact allergies to the preservatives formaldehyde and methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) have been reported to appear together at a statistically significant level. Recently, revisions concerning the patch test preparations of MCI/MI, MI and formaldehyde have been recommended for the European baseline series.To investigate ...
Ann, Pontén +4 more
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Contact allergies to the preservatives formaldehyde and methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) have been reported to appear together at a statistically significant level. Recently, revisions concerning the patch test preparations of MCI/MI, MI and formaldehyde have been recommended for the European baseline series.To investigate ...
Ann, Pontén +4 more
openaire +1 more source
Methylisothiazolinone sensitisation in New Zealand is decreasing
Australasian Journal of DermatologyAbstractBackground/ObjectivesIn the last 10 years methylisothiazolinone (MI) emerged as a global cause of preservative‐related ACD. New Zealand has liberal regulations for the MI concentration limit in cosmetic products compared to Europe and Australia.
Hyun Kyoung Lee, Harriet Kennedy
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