Results 11 to 20 of about 981 (151)

Isothiazolinones in Disposable Rubber Gloves-Results of Chemical Analysis. [PDF]

Contact Dermatitis
Chemical analysis revealed benzisothiazolinone (BIT) in 30/54 disposable rubber gloves (27 nitrile rubber gloves, 2 neoprene rubber gloves and 1 natural rubber glove) in concentrations of 0.3–73.7 ppm. Methylisothiazolinone (MI) was found in six nitrile rubber gloves in small concentrations.
Suuronen K, Ylinen K, Suomela S, Pesonen M.   +3 more
europepmc   +2 more sources

Skin Barrier Biomarkers in Patch-Induced and Clinical Allergic and Irritant Contact Dermatitis. [PDF]

Contact Dermatitis
Both patch‐induced and clinical ICD and ACD showed consistent alterations in skin barrier‐associated biomarkers, indicative of skin barrier impairment. Among the tested allergens, chromium elicited more pronounced biomarker responses compared to nickel and methylisothiazolinone.
Kezic S, de Boer F, Metwally NKA, Vlugt KG, Beers-Stet FS, Ouwerkerk W, Jakasa I, Rustemeyer T, van der Molen HF.   +8 more
europepmc   +2 more sources

Genetic Insights Into Allergic Contact Dermatitis: Reassessing the Role of LCE3C_LCE3B Deletion. [PDF]

Contact Dermatitis
This study found no significant association between the LCE3C_LCE3B deletion and allergic contact dermatitis or polysensitisation in Tunisian patients, suggesting that other genetic or environmental factors may contribute to disease susceptibility. ABSTRACT Background Allergic contact dermatitis (ACD) is a multifactorial inflammatory skin disorder ...
Ben Lamine Z, Moussa A, Bouhoula M, Gerisha R, Sabbagh S, Kacem I, Aloui A, Chatti S, Brahem A, Zemni R, Ben Hadj Slama F.   +10 more
europepmc   +2 more sources

Contact Allergy to Ingredients of Hair Cosmetics Associated with Occupational and Non-Occupational Exposure-Trends from 1995 to 2020 in Central Europe, with or without Regulation. [PDF]

Contact Dermatitis
Among 2678 female hairdressers and 6244 female consumers with contact dermatitis suspected to be related to use of hair cosmetics, including dyes, patch tested in the IVDK between 1995 and 2020, diverging contact allergy trends were observed. In the case of toluene‐2,5‐diamine (PTD) shown in the figure, sensitization was at a stable, high level in ...
Uter W, Schwensen JFB, Blömeke B, Gefeller O, John SM, Bieck C, Schubert S.   +6 more
europepmc   +2 more sources

Axillary Contact Dermatitis in an Adult Caused by Hexamidine Diisethionate From Baby Wipes Labelled "Pure Water". [PDF]

Contact Dermatitis
Contact Dermatitis, Volume 94, Issue 2, Page 190-191, February 2026.
Domingos-Ancement EE, Misery L, Deydier N.   +2 more
europepmc   +2 more sources

Eye irritation tests of polyhexamethylene guanidine phosphate (PHMG) and chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a tissue model of reconstructed human cornea-like epithelium [PDF]

Environmental Health and Toxicology, 2019
Disinfectants including polyhexamethylene guanidine phosphate (PHMG) and mixtures of chloromethylisothiazolinone/ methylisothiazolinone (CMIT/MIT) have been widely used in Korea to prevent microbial growth in the humidifier water, which triggered an ...
Juyoung Park, Handule Lee, Kwangsik Park
doaj   +1 more source

Quantification of Methylisothiazolinone and Methylchloroisothiazolinone Preservatives by High-Performance Liquid Chromatography

Molecules, 2023
Isothiazolinone preservatives (methylisothiazolinone (MIT) and methylchloroisothiazolinone (CMIT) are commonly used in cosmetics, industrial and household products. However, these isothiazolinone derivatives are known to cause allergic contact dermatitis.
Samyah Alanazi, Hajera Tabassum, Manal Abudawood, Reem Alrashoudi, May Alrashed, Yazeed A. Alsheikh, Salma Alkaff, Manal Alghamdi, Naif Alenzi   +8 more
doaj   +1 more source

Allergy to isothiazolinones in recent years

Medycyna Pracy, 2020
Background Isothiazolinones are preservatives which are present in cosmetics, household chemicals and many other industrial products. Initially, a mixture of methylchloroisothiazolinone and methylisothiazolinone (MCI/MI – Kathon CG) was used, and then ...
Ewa Nowakowska-Świrta, Marta Kieć-Świerczyńska   +1 more
doaj   +1 more source

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019-2024. [PDF]

Contact Dermatitis
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Grau-Pérez M, Mercader-García P, Giménez-Arnau AM, Sanz-Sánchez T, Ninet VZ, Guijarro SC, Miquel FJM, Salvador JFS, González-Pérez R, González IR, Baldrich ES, Carrascosa JM, de Frutos FJO, Serna MR, Ortega MEG, Suárez CP, Triviño FJN, Chicharro P, Andreu M, Gilo AS, Pereyra Rodríguez JJ, Nieto MAP, Melé-Ninot G, Guillén PS, de la Fuente EG, Elosua-González M, Munera-Campos M, Romero FT, Descalzo MÁ, Borrego L.   +29 more
europepmc   +2 more sources

T helper and IL-20 cytokine signatures distinguish atopic dermatitis from contact dermatitis subtypes. [PDF]

J Eur Acad Dermatol Venereol
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 510-512, March 2026.
De Greef A, Puigdevall L, de Montjoye L, Herman A, Hendrickx E, Dumoutier L, Baeck M.   +6 more
europepmc   +2 more sources