Results 151 to 160 of about 2,693,074 (200)
FOXA2-initiated transcriptional activation of INHBA induced by methylmalonic acid promotes pancreatic neuroendocrine neoplasm progression. [PDF]
Cell Mol Life SciHu C +13 more
europepmc +1 more source
Increased serum methylmalonic acid levels were associated with the presence of cognitive dysfunction in older chronic kidney disease patients with albuminuria. [PDF]
BMC GeriatrZhang J, Wu L, Wang S, Pan Y, Zhang A.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Methylmalonic Acid — An Endogenous Toxin?
Cellular and Molecular Life Sciences, 2005Methylmalonic acid was previously considered as major neurotoxin in methylmalonic acidurias. In contrast, recent studies support the notion that other metabolites deriving from propionyl-coenzyme A, inducing synergistic inhibition of mitochondrial energy metabolism, are more important than methylmalonic acid to understand the neuropathogenesis of this ...
Stefan Kolker, J G Okun
exaly +3 more sources
Pediatric Transplantation, 2010
Methylmalonic acidemia with complete mutase deficiency (mut(0) type) is an inborn error of metabolism with high mortality and morbidity. LT has been suggested to be a solution to this disease, but elevation of urinary and blood MMA was still observed after LT.
P H Lee, W L Hwu, Y H Ni
exaly +3 more sources
Methylmalonic acidemia with complete mutase deficiency (mut(0) type) is an inborn error of metabolism with high mortality and morbidity. LT has been suggested to be a solution to this disease, but elevation of urinary and blood MMA was still observed after LT.
P H Lee, W L Hwu, Y H Ni
exaly +3 more sources
Metabolic Precursors of Methylmalonic Acid in Vitamin-B12 Deficiency.
Lancet, The, 1967Abstract Valine, isoleucine and sodium propionate have been investigated as precursors of urinary methylmalonic acid in patients with vitamin B12 deficiency. Valine was administered to fifteen patients with vitamin B12 deficiency and provoked an increased excretion of methylmalonic acid in all cases. The same dose of valine had no effect on excretion
J H Jones
exaly +4 more sources
Ascorbic acid and α-tocopherol attenuate methylmalonic acid-induced convulsions
NeuroReport, 1999 The effects of chronic administration of alpha-tocopherol or melatonin, or acute ascorbic acid administration on the convulsant action of methylmalonic acid (MMA) were investigated in adult male rats. Animals were chronically injected with alpha-tocopherol (40 mg kg(-1), i.p.), melatonin (5 mg kg(-1), i.p.) or vehicle for 7 days.
Fighera, M. R. +7 more
openaire +4 more sources
Diagnostic Performances of Urinary Methylmalonic Acid/Creatinine Ratio in Vitamin B12 Deficiency
Journal of Clinical Medicine, 2020 Sole measurement of plasma vitamin B12 is no longer enough to identify vitamin B12 (B12) deficiency. When plasma vitamin B12 is in the low-normal range, especially between 201 and 350 ng/L, B12 deficiency should be assessed by measurements of plasma ...
Geoffrey Urbanski +2 more
exaly +2 more sources
Methylmalonic Acid Excretion Studies
British Journal of Haematology, 1973Summary. Oral valine and isoleucine were equally effective in producing an increased urinary excretion of methylmalonic acid (MMA) in vitamin B12 deficiency but oral MMA itself, methionine and leucine were unsatisfactory.MMA excretion was increased in 16 out of 23 patients with vitamin B12 deficiency after valine and/or isoleucine loading but remained
I, Chanarin +3 more
openaire +2 more sources
Serum methylmalonic acid in uraemia
Scandinavian Journal of Clinical and Laboratory Investigation, 1992During a 3 month period we measured serum methylmalonic acid concentrations monthly in 37 patients, all on chronic haemodialysis because of end-stage kidney disease. Concentrations of methylmalonic acid in serum were above the upper reference limit in 36 of the 37 subjects.
L, Moelby, K, Rasmussen, H H, Rasmussen
openaire +2 more sources
Pediatrics, 1973
Methylmalonate studies have led to some understanding of vitamin B12 metabolism as well as certain inborn errors of metabolism. These, in turn, have served as models of a group of diseases related to acidosis, so that the study of organic aciduria at present is similar to that of amino aciduria 20 years ago.
openaire +2 more sources
Methylmalonate studies have led to some understanding of vitamin B12 metabolism as well as certain inborn errors of metabolism. These, in turn, have served as models of a group of diseases related to acidosis, so that the study of organic aciduria at present is similar to that of amino aciduria 20 years ago.
openaire +2 more sources