Results 61 to 70 of about 2,693,074 (200)

Serum cobalamin and methylmalonic acid concentrations in juvenile dogs with parvoviral enteritis or other acute enteropathies

Journal of Veterinary Internal Medicine, 2023
Background Low serum cobalamin concentrations have been associated with ileal malabsorption in dogs with chronic enteropathy. Increased serum methylmalonic acid (MMA) concentrations indicate cobalamin deficiency on a cellular level.
Michael Hung, Justin Heinz, Jӧrg M. Steiner, Jan Suchodolski, Jonathan Lidbury   +4 more
doaj   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3959-3971, November 2026.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Lower‐Limb‐Predominant Axonal Sensorimotor Polyneuropathy With Severe Proximal Weakness and Possible Myopathic Involvement After Sleeve Gastrectomy: A Case Report of Delayed Recognition

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Bariatric surgery is increasingly performed in adolescents and young adults. Although sleeve gastrectomy preserves intestinal continuity and is often regarded as nutritionally low‐risk, it can still precipitate micronutrient deficiency, and obesity itself predisposes to thiamine deficiency, which can cause both Wernicke encephalopathy and a ...
Altin Kuqo, Floreta Kurti, Erand Llanaj
wiley   +1 more source

Essential Oral Single Nutritional Therapy Products for Inherited Metabolic Diseases: Evidence and Consensus Assessment Using a Modified Delphi Method

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk, Bart M. F. Penninx, Annet M. Bosch, Mirjam Langeveld, Gajja S. Salomons, Carla E. M. Hollak, Essential Nutritional Therapy Products for IMDs Consensus Group, Dorothea Möslinger, Saskia Wortmann, David Cassiman, Pavel Ješina, Jiri Zeman, Allan M. Lund, François Feillet, Nazi Tabatadze, Sarah C. Grünert, Anke Schumann, Ute Spiekerkoetter, Ulrike Mütze, Thomas Opladen, Anastasia Skouma, Ina Knerr, Serena Gasperini, Vincenza Gragnaniello, Mariarosa (Marina) Anna Beatrice Melone, Francesca Nardecchia, Alessandro La Rosa, Birutė Tumienė, Margreet Wagenmakers, Terry Derks, Camilla Tøndel, Beata Kieć‐Wilk, Urh Groselj, Amaya Bélanger‐Quintana, Javier De las Heras, Mireia del Toro Riera, Eva Venegas Moreno, Matthias Gautschi, Johannes Häberle, Elaine Murphy   +39 more
wiley   +1 more source

Methylmalonic acidemia with recurrent hemophagocytic lymphohistiocytosis: a case report and review of the literature

BMC Pediatrics
Background Methylmalonic acidemia is a rare autosomal recessive disorder of propionate catabolism characterized by the accumulation of propionic acid and methylmalonic acid caused by methylmalonyl-CoA mutase deficiency.
Fumiya Yamashita, Satoshi Akamine, Pin Fee Chong, Kenichi Maeda, Saori Kawakami, Sooyoung Lee, Masataka Ishimura, Kei Murayama, Yasunari Sakai, Ryutaro Kira   +9 more
doaj   +1 more source

The Reaction of Methylmalonic Acid with Aldehydes

Nippon kagaku zassi, 1962
π-プチルアルデヒド,π-ヘプタアルデヒド,およびρ-ニトロベンズァルデヒドをメチルマロン酸とピリジンまたはトリェチルアミンの存在で反応させた。反応は脱炭酸のみをともない,α-メチル-β-オキシカルボン酸が生成された。このオキセ酸を85%硫酸中でラクトン化させてα-メチル-γ-カプロラクトンおよび-γ-η-ノナラクトンが得られた。
openaire   +2 more sources

A Technique for Measurement of Methylmalonic Acid in Cattle Urine

Journal of Dairy Science, 1977
Methylmalonic acid was measured in cattle urine by decarboxylating it to propionate with sulfuric acid and heat and quantifying the propionate so formed by gas-liquid chromatography. Crystalline methylmalonic acid added to cow urine was recovered quantitatively.
E P, Barton, J M, Elliot
openaire   +2 more sources

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

Comparison of tissue and plasma methylmalonic acid levels in the MMA stop codon rescue mice.

, 2013
Tissue results presented as mean µmol/g tissue ± SEM (n = 8). Control samples had less than 15 µmol/g tissue. Plasma results presented as mean concentration (µmol/L) ± SEM (n = 8), control plasma samples had less than 1 µmol/L methylmalonic acid.
Leonie R. Wood (307547), Heidi L. Peters (307548), James J. Pitt (307546), Harriet Dashnow (307545), Nicole E. Buck (307544)   +4 more
core   +1 more source

Hypocortisolaemia with gastrointestinal haemorrhage in a young cat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐month‐old, female, spayed domestic shorthair presented with a 1‐week history of lethargy and anorexia. On admission, the cat had severe hypoglycaemia, and hypovolaemic and distributive shock were suspected. Mucosal defects identified by ultrasonography were suggestive of gastrointestinal ulceration.
Victoria J. Skinner, Bronwyn Zimmerman, Ivayla D. Yozova   +2 more
wiley   +1 more source