Adolescent D-amphetamine treatment in a rodent model of ADHD: pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood [PDF]
, 2016 Attention-deficit/hyperactivity disorder (ADHD) is comorbid with cocaine abuse. Whereas initiating ADHD medication in childhood does not alter later cocaine abuse risk, initiating medication during adolescence may increase risk.
Dwoskin, Linda P. +3 more
core +1 more source
The Impact of Methylphenidate on Sexual Functions: A Systematic Review of Benefits and Risks
PharmaceuticalsBackground: Methylphenidate is a psychostimulant that enhances dopamine and norepinephrine neurotransmission through the mechanism of reuptake inhibition at the synaptic cleft.
Rafał Bieś +4 more
doaj +1 more source
Narcolepsy and rapid eye movement sleep
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini +4 more
wiley +1 more source
Actigraphic Recording of Manic Symptoms Induced by Methylphenidate
Case Reports in Medicine, 2009 Objective. Attention-deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by a long-standing pattern of impulsive behavior, hyperkinesia, and inattention.
Tuuli Lahti +3 more
doaj +1 more source
Sleep Reactivity Amplifies the Impact of Pre‐Sleep Cognitive Arousal on Sleep Disturbances
Journal of Sleep Research, EarlyView.This study investigates how sleep reactivity moderates the ‘stress‐pre‐sleep arousal‐sleep’ pathway in university students. At the within‐individual level, both high and low sleep‐reactive groups showed increased pre‐sleep cognitive arousal and sleep disruptions in response to elevated daily stress.
Noof Abdullah Saad Shaif +5 more
wiley +1 more source
A comprehensive investigation of memory impairment in attention deficit hyperactivity disorder and oppositional defiant disorder [PDF]
, 2012 We conducted a comprehensive and systematic assessment of memory functioning indrug-naïve boys with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD).
Alloway +55 more
core +1 more source
Evaluation of bone mineral density in rats administered methylphenidate
Psychiatry and Clinical Psychopharmacology, 2021 Objective: Methylphenidate is a drug which is frequently prescribed in order to cope with the symptoms of attention-deficit hyperactivity disorder.
Tümer Türkbay +4 more
doaj
Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies
Psychiatry and Clinical Neurosciences, EarlyView.Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda +4 more
wiley +1 more source
Catecholamine-Based Treatment in AD Patients: Expectations and Delusions. [PDF]
, 2015 In Alzheimer disease, the gap between excellence of diagnostics and efficacy of therapy is wide. Despite sophisticated imaging and biochemical markers, the efficacy of available therapeutic options is limited.
Alessandro eStefani +9 more
core +3 more sources