Results 81 to 90 of about 40,562 (182)
Psychiatry and Clinical Neurosciences, Volume 79, Issue 5, Page 257-265, May 2025.Aim Vafidemstat is a brain‐penetrant, orally bioavailable, small molecule irreversible inhibitor of the histone lysine‐specific demethylase KDM1A (also known as LSD1), which corrects memory deficits and behavior alterations including aggression and social interaction deficits in preclinical models.
Marc Ferrer +9 more
wiley +1 more source
Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects [PDF]
, 2014 3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate are widely used psychoactive substances. MDMA primarily enhances serotonergic neurotransmission, and methylphenidate increases dopamine but has no serotonergic effects.
Hysek, Cédric M. +6 more
core +1 more source
Brain iron load and neuroaxonal vulnerability in adult attention‐deficit hyperactivity disorder
Psychiatry and Clinical Neurosciences, Volume 79, Issue 5, Page 282-289, May 2025.Aim Adult attention deficit hyperactivity disorder (ADHD) may be associated with an increased risk of dementia in old age. Here, we investigated the liability for neurodegenerative brain disease in adult ADHD, possibly reflected by increased brain iron content and associated neuroaxonal vulnerability. Methods Thirty‐two adults with ADHD (35 ± 10 years)
Jatta Berberat +13 more
wiley +1 more source
Pharmaceutical Neuroenhancement in the Quest for Worth at Work
Sociological Inquiry, EarlyView.This article examines the use of psychoactive substances for cognitive enhancement in the context of work. By drawing upon existing qualitative research and sociological theories on meaningful work, valuation, and human agency, I explore cultural and institutional processes encouraging individuals to engage in such practices and argue that ...
Sigita Doblytė
wiley +1 more source
Acute and long-term effects elicited by psychoactive drugs on 50-kHz ultrasonic vocalizations in rats: development of a new experimental tool for the study of drug-mediated reward. [PDF]
, 2014 Ultrasonic vocalizations (USVs) have recently emerged as an indicator of the emotional state of rats, and the evaluation of the USVs in the 50-kHz range has been proposed as a tool to investigate the affective properties of drugs of abuse.
SIMOLA N
core
Acta Psychiatrica Scandinavica, Volume 152, Issue 1, Page 27-38, July 2025.ABSTRACT Introduction Rises in prevalence and incidence of the neurodevelopmental disorder Attention‐deficit/Hyperactivity Disorder (ADHD) have been reported globally and estimated in Denmark previously. Nevertheless, differences in methodology hinder an assessment of the temporal evolution of ADHD based on published literature.
Simon Grøntved +5 more
wiley +1 more source
Addiction, Volume 120, Issue 7, Page 1345-1359, July 2025.Abstract Aims This study tested the efficacy and safety of a 12‐week course of lisdexamfetamine in reducing methamphetamine use, an outcome which is associated with improvements in health and wellbeing, in people dependent on methamphetamine. Design, setting and participants This study was a randomised double‐blind placebo‐controlled trial conducted in
Nadine Ezard +24 more
wiley +1 more source
METHYLPHENIDATE INDUCED ECCHYMOSIS
Psychiatria Danubina, 2021 Şahan, Ebru, Boylu, MUHAMMED EMİN
openaire +4 more sources
Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.This study aimed to assess the efficacy and safety of SDT‐001, a digital therapeutic, in Japanese children and adolescents with attention‐deficit/hyperactivity disorder (ADHD). The SDT‐001 group tended to show a greater change from baseline in the ADHD‐RS‐IV scores than the single‐task group, but this difference was not statistically significant ...
Katsunaka Mikami +6 more
wiley +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.Abstract Background Recent studies have shown that sleep disturbances are frequent at different stages of psychosis, including clinical high risk for psychosis (CHR‐P). However, the comorbidity of hypersomnia with CHR‐P and its treatment have rarely been reported or discussed.
Yutaro Sato +2 more
wiley +1 more source