Results 121 to 130 of about 167,693 (338)

Early therapies for acute traumatic spinal cord injury

open access: yesRomanian Neurosurgery, 2013
Early therapies for acute traumatic spinal cord injury has some key points: 1. Immediately or soon after the injury is recommended a hemodynamic support to maintain mean arterial pressure at 85 – 90 mmHg and monitoring in an intensive care unit for the ...
St. M. Iencean   +3 more
doaj  

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Synthesis of methylprednisolone loaded ibuprofen modified dextran based nanoparticles and their application for drug delivery in acute spinal cord injury

open access: yesOncoTarget, 2017
To improve the therapeutic efficacy of spinal cord injury (SCI), the methylprednisolone was incorporated into nanoparticles based on the ibuprofen modified dextran.
Lei Qi   +6 more
semanticscholar   +1 more source

Clinical Images: Acute vision loss due to granulomatosis with polyangiitis

open access: yes
Arthritis &Rheumatology, EarlyView.
Hirotaka Yamamoto, Yoshinori Taniguchi
wiley   +1 more source

Prevalence of Actionable Pharmacogenetic Genotype Frequencies, Cautionary Medication Use, and Polypharmacy in Community‐Dwelling Older Adults

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman   +14 more
wiley   +1 more source

Methylprednisolone promotes recovery of neurological function after spinal cord injury: association with Wnt/β-catenin signaling pathway activation

open access: yesNeural Regeneration Research, 2016
Some studies have indicated that the Wnt/β-catenin signaling pathway is activated following spinal cord injury, and expression levels of specific proteins, including low-density lipoprotein receptor related protein-6 phosphorylation, β-catenin, and ...
Gongbiao Lu   +8 more
semanticscholar   +1 more source

Fused-core HPLC method development implemented in a short-term stability study of Triple IT solution [PDF]

open access: yes, 2011
For the majority of children with acute lymphoblastic leukemia (ALL), treatment consists in part of a triple intrathecal (Triple IT) therapy, i.e. a combination of cytarabine (CB), methotrexate (MTX) and methylprednisolone sodium succinate (MPSS) [1 ...
Bauters, Tieneke   +7 more
core  

Comparison of the efficacy of low doses of methylprednisolone, acetaminophen, and dexketoprofen trometamol on the swelling developed after the removal of impacted third molar [PDF]

open access: yes, 2015
Background: The aim of the present study was to compare the efficacy of low doses of methylprednisolone, acetaminophen and dexketoprofen trometamol, which are among the drug groups used in our clinic, on postoperative swelling developing after removal ...
Ataoglu, Hanife   +3 more
core   +1 more source

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