Results 271 to 280 of about 167,693 (338)

A Rare Case Report of an Adult With Intraspinal Gouty Stones and Concurrent Knee Joint Involvement

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT This case highlights the importance of considering spinal gout in patients with hyperuricemia presenting with atypical back pain or neurological symptoms. Multidisciplinary surgical management, including decompression and joint arthroscopy, combined with urate‐lowering therapy and lifestyle modifications, can achieve significant symptom relief
Bo Cao, Jinlong Wang
wiley   +1 more source

Innovative Use of Fostamatinib in Managing Refractory Immune Thrombocytopenia in an HIV‐Positive Patient: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Managing immune thrombocytopenia (ITP) in HIV patients remains challenging due to refractory cases and treatment limitations. This report highlights fostamatinib as a safe, effective, and antiretroviral therapy‐compatible option, offering durable platelet stabilization in a difficult‐to‐treat population.
Matteo Bellia   +8 more
wiley   +1 more source

Methylprednisolone Protects Human Pancreatic Beta Cells From Inflammation-induced Damage. [PDF]

open access: yesTransplant Direct
Paz-Barba M   +4 more
europepmc   +1 more source

Uncovering New Therapeutic Targets for Amyotrophic Lateral Sclerosis and Neurological Diseases Using Real‐World Data

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 242-251, July 2025.
Although attractive for relevance to real‐world scenarios, real‐world data (RWD) is typically used for drug repurposing and not therapeutic target discovery. Repurposing studies have identified few effective options in neurological diseases such as the rare disease, amyotrophic lateral sclerosis (ALS), which has no disease‐modifying treatments ...
Mohammadali Alidoost   +9 more
wiley   +1 more source

The effect of pre‐operative methylprednisolone on early endothelial damage after total knee arthroplasty: a randomised, double‐blind, placebo‐controlled trial

open access: yesAnaesthesia, 2017
Viktoria Lindberg-Larsen   +6 more
semanticscholar   +1 more source

Enfortumab Vedotin–Induced Toxic Epidermal Necrolysis in Metastatic Urothelial Carcinoma Complicated by Severe Gastrointestinal Bleeding

open access: yesIJU Case Reports, Volume 8, Issue 4, Page 348-351, July 2025.
ABSTRACT Introduction Enfortumab vedotin (EV) has been reported to cause skin toxicity in some patients. We report a rare case of toxic epidermal necrolysis (TEN) induced by EV and complicated by severe gastrointestinal (GI) bleeding. Case Presentation A 70‐year‐old man with recurrent urothelial carcinoma developed a trunk rash at 16 days after EV ...
Aika Matsuyama   +9 more
wiley   +1 more source

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