Results 251 to 260 of about 32,814 (296)
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Metoclopramide-Induced Agranulocytosis
Annals of Internal Medicine, 1988Excerpt Adverse side effects occur in up to 20% of patients receiving metoclopramide treatment (Reglan, A.H. Robbins Co., Richmond, Virginia) (1).
Michael J. Luzar, Roger L. Harvey
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Metoclopramide in Parkinson's disease
Clinical Pharmacology & Therapeutics, 1978The effect of metoclopramide given in a dose of 10 mg or 20 mg 3 times a day has been compared with placebo in a double‐blind randomized crossover study in 11 treated parkinsonian patients. Effects on blood pressure, parkinsonian symptoms and signs, and psychopathologic features were measured. There was no significant effect of metoclopramide at either
N. J. Legg +3 more
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Clinical Pharmacokinetics of Metoclopramide
Clinical Pharmacokinetics, 1983Metoclopramide is rapidly and well absorbed from the gastrointestinal tract, and in man undergoes variable first-pass metabolism (oral bioavailability 32 to 100%). In man, N-4 sulphate conjugation is an important pathway of metabolism and after oral administration the ratio of free to conjugated metoclopramide in urine correlates with the plasma AUC ...
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Metoclopramide-Induced Methemoglobinemia
Pediatrics, 1988The case of a 3-week-old male infant is described. After receiving an iatrogenic overdose of metoclopramide (1.0 mg/kg every six hours) throughout a 36-hour period for the treatment of suspected gastroesophageal reflux, he became cyanotic, lethargic, and irritable, he fed poorly, and he had diarrhea and respiratory distress.
Gregory L. Kearns, Debra H. Fiser
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Metoclopramide toxicity in an infant
Pediatric Emergency Care, 1998Metoclopramide (4-amino-5-chloro-N-2-methoxybenzamide) is a central and peripheral acting dopamine antagonist. It also stimulates motility in the upper gastrointestinal tract and increases lower esophageal sphincter pressure. In the pediatric population, it is used extensively as an antiemetic and in the treatment of gastroesophageal reflux disease ...
Keith F. Batts, David W. Munter
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Metoclopramide and Gastric Stasis
Annals of Internal Medicine, 1982Excerpt To the editor: The recent double-blind, controlled study by Snape and associates (1), which showed the superiority of oral metoclopramide versus placebo in relieving symptoms of gastric sta...
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Annals of Internal Medicine, 1982
Excerpt To the editor: Metoclopramide, a central dopamine receptor antagonist, has potent cholinergic stimulatory effects on the gastrointestinal tract and is used for a variety of motility related...
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Excerpt To the editor: Metoclopramide, a central dopamine receptor antagonist, has potent cholinergic stimulatory effects on the gastrointestinal tract and is used for a variety of motility related...
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Annals of Internal Medicine, 1983
Excerpt To the editor: The review (1) of the pharmacology of metoclopramide touched so briefly on its effects on plasma aldosterone levels (2) to imply that these effects are of no clinical signifi...
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Excerpt To the editor: The review (1) of the pharmacology of metoclopramide touched so briefly on its effects on plasma aldosterone levels (2) to imply that these effects are of no clinical signifi...
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