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Coupling of synchronous fluorescence spectroscopy with derivative amplitude outcomes for simultaneous determination of metoprolol succinate and olmesartan medoxomil in combined pharmaceutical preparation: Application in spiked human plasma.

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2023
For the first time a spectrofluorimetric method had been achieved for the concurrent analysis of metoprolol succinate (MET) and olmesartan medoxomil (OLM). The approach depended on assessing the first order derivative (1D) of the synchronous fluorescence
Amira H. Kamal   +2 more
semanticscholar   +1 more source

A new polymorphic form of metoprolol succinate

Pharmaceutical Development and Technology, 2016
Only one crystal form of metoprolol succinate (Form I) was reported during previous researches and production. In this study, a new polymorph of metoprolol succinate (here named as Form II) was discovered and investigated by X-ray diffraction, thermoanalysis and infrared spectroscopy.
Mengqing, Zhou   +6 more
openaire   +2 more sources

Abstract 4368357: Comparative 2 Year Outcomes of Carvedilol Versus Metoprolol Succinate initiation in Heart failure with reduced ejection fraction Patients with End-Stage Renal Disease on Dialysis: A Propensity- Matched analysis

Circulation
Background: Heart failure with reduced ejection fraction (HFrEF) in patients with end-stage renal disease (ESRD) on dialysis is associated with high morbidity and mortality.
Efeturi Okorigba   +6 more
semanticscholar   +1 more source

Metoprolol Succinate Combination in the Treatment of Hypertension

Angiology, 2008
Metoprolol is a selective β(l)-adrenergic antagonist extensively used since 1975. Metoprolol has proven its efficacy in reducing cardiovascular events and mortality in patients with hypertension and coronary heart disease. A recently developed controlled release/extended-release formulation of metoprolol succinate was designed to provide relatively ...
Dimitris P, Papadopoulos   +1 more
openaire   +2 more sources

A Novel RP-HPLC Method for the Development and Validation of Metoprolol Succinate in Bulk and Pharmaceutical Dosage Form

Asian Journal of Pharmaceutical Analysis
The objective of the present study was to develop and validate a simple, accurate, and robust reverse-phase high-performance liquid chromatographic (RP-HPLC) method for the estimation of Metoprolol Succinate in bulk drug and marketed formulations ...
Hemangi Somnath Chaudhari   +1 more
semanticscholar   +1 more source

Development and Validation of UV Spectroscopic Method for Simultaneous Estimation of Metoprolol Succinate and Cilostazol

Asian Journal of Pharmaceutical Analysis
In the present work, A Simple, rapid, sensitive, precise, and reproducible, specific UV spectrophotometric method for the determination of Metoprolol succinate and Cilostazol in bulk drug form were developed and validated.
Abhishek Chauhan   +3 more
semanticscholar   +1 more source

Abstract 4371485: One-Year Outcomes of Bisoprolol vs Metoprolol Succinate in Patients with Heart failure with reduced ejection fraction and End Stage Kidney Disease: A Propensity-Matched Study

Circulation
Background: Patients with heart failure with reduced ejection fraction (HFrEF) and end-stage renal disease (ESRD) represent a high-risk population in whom optimal beta-blocker selection remains unclear.
Efeturi Okorigba   +6 more
semanticscholar   +1 more source

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