Results 21 to 30 of about 19,037 (261)
Nordic Wittgenstein Review, 2023 Recently, Irad Kimhi has argued that negation and falsehood can be made intelligible by understanding assertions/judgements as acts of two-way logical capacities.
Thomas Henry Raysmith
doaj +1 more source
The Russian iambic tetrameter: The problem of description (Prolegomena to a new paradigm)
Studia Metrica et Poetica, 2016 From the very beginning of systematic investigation of the Russian iambic tetrameter (1910s–1940s), the proportion of stresses on the first and second ictus of the line was chosen as its main rhythmic characteristic.
Sergei Liapin
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Development of smart energy monitoring using NB-IOT and cloud
Measurement: Sensors, 2023 IoT-based applications are growing in popularity nowadays because they offer effective answers to numerous current problems. In this research, With the aim of decreasing human efforts for monitoring the power units and increasing users' knowledge of ...
R.V. Siva Balan +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
SELIMBook review of Burns, Rachel A., and Rafael J. Pascual, eds. 2022. Tradition and Innovation in Old English Metre. Leeds: Arc Humanities Press. Pp. xii + 281. ISBN 1802700250.
Daniel Donoghue
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source