Results 61 to 70 of about 70,935 (267)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Connected Sum Construction for σ k -Yamabe Metrics [PDF]

open access: yesJournal of Geometric Analysis, 2011
In this paper we produce families of Riemannian metrics with positive constant $σ_k$-curvature equal to $2^{-k} {n \choose k}$ by performing the connected sum of two given compact {\em non degenerate} $n$--dimensional solutions $(M_1,g_1)$ and $(M_2,g_2)$ of the (positive) $σ_k$-Yamabe problem, provided $2 \leq 2k < n$.
CATINO, GIOVANNI, L. Mazzieri
openaire   +6 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

DDVV Inequality on Submanifolds Coupled with a Slant Factor in Quaternionic Kaehler Manifolds

open access: yesAxioms
This work aims to provide generalized Wintgen inequalities for slant submanifolds embedded in quaternionic space forms, taking into consideration both semi-symmetric metric and semi-symmetric non-metric connections.
Rawan Bossly   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

On Ricci Solitons and Curvature Properties of Doubly Warped Products with QSMC

open access: yesAxioms
This paper explores the geometric interplay between the Levi–Civita connection and the quarter-symmetric metric connection on doubly warped product manifolds.
Md Aquib   +3 more
doaj   +1 more source

Node self‐connections in network metrics [PDF]

open access: yesEcology Letters, 2017
AbstractZamborain‐Mason et al. (Ecol. Lett., 20, 2017, 815–831) state that they have newly proposed network metrics that account for node self‐connections. Network metrics incorporating node self‐connections, also referred to as intranode (intrapatch) connectivity, were however already proposed before and have been widely used in a variety of ...
openaire   +2 more sources

New Metric and Connections in Statistical Manifolds [PDF]

open access: yes, 2015
We define a metric and a family of $α$-connections in statistical manifolds, based on $φ$-divergence, which emerges in the framework of $φ$-families of probability distributions. This metric and $α$-connections generalize the Fisher information metric and Amari's $α$-connections.
Rui Facundo Vigelis   +2 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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