Results 81 to 90 of about 510,591 (285)

A metric approach to limit operators

, 2016
We extend the limit operator machinery of Rabinovich, Roch, and Silbermann from Z^N to (bounded geometry, strongly) discrete metric spaces. We do not assume the presence of any group structure or action on our metric spaces.
Spakula, Jan, Willett, Rufus
core   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Cubic Differentials in the Differential Geometry of Surfaces [PDF]

, 2017
We discuss the local differential geometry of convex affine spheres in $\re^3$ and of minimal Lagrangian surfaces in Hermitian symmetric spaces. In each case, there is a natural metric and cubic differential holomorphic with respect to the induced ...
Loftin, John, McIntosh, Ian
core  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Vortices and Jacobian varieties

, 2010
We investigate the geometry of the moduli space of N-vortices on line bundles over a closed Riemann surface of genus g > 1, in the little explored situation where 1 =< N < g. In the regime where the area of the surface is just large enough to accommodate
Arbarello, Ballmann, Baptista, Baptista, Bergman, Bogomolny, Bradlow, Bökstedt, Donaldson, Dunne, Faltings, Farkas, Frenkel, García-Prada, Griffiths, Hitchin, Jaffe, Jost, Kobayashi, Krantz, Lewittes, Manton, Manton, Manton, Manton, Manton, Mumford, Nasir, Nicholas S. Manton, Nuno M. Romão, Reid, Samols, Stuart, Tong, Yang   +34 more
core   +1 more source

Metric-Affine Geometries with Spherical Symmetry [PDF]

Symmetry, 2020
We provide a comprehensive overview of metric-affine geometries with spherical symmetry, which may be used in order to solve the field equations for generic gravity theories which employ these geometries as their field variables. We discuss the most general class of such geometries, which we display both in the metric-Palatini formulation and in the ...
openaire   +2 more sources

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Exploring compact stellar structures in Finsler–Randers geometry with the Barthel connection

European Physical Journal C: Particles and Fields
This study introduces a pioneering approach to analyzing compact stars through Finslerian geometry, which has not been previously explored in this context.
J. Praveen, S. K. Narasimhamurthy, B. R. Yashwanth   +2 more
doaj   +1 more source

Transition to light-like trajectories in thin shell dynamics

Nuclear Physics B, 2018
It was recently shown that a massive thin shell that is sandwiched between a flat interior and an exterior geometry given by the outgoing Vaidya metric becomes null in a finite proper time.
Robert B. Mann, Ian Nagle, Daniel R. Terno   +2 more
doaj   +1 more source