Results 41 to 50 of about 41,328 (259)

Curvature exponent and geodesic dimension on Sard-regular Carnot groups

Analysis and Geometry in Metric Spaces
In this study, we characterize the geodesic dimension NGEO{N}_{{\rm{GEO}}} and give a new lower bound to the curvature exponent NCE{N}_{{\rm{CE}}} on Sard-regular Carnot groups.
Golo Sebastiano Nicolussi, Zhang Ye
doaj   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Metric quasiconformality and Sobolev regularity in non-Ahlfors regular spaces

Analysis and Geometry in Metric Spaces
Given a homeomorphism f:X→Yf:X\to Y between QQ-dimensional spaces X,YX,Y, we show that ff satisfying the metric definition of quasiconformality outside suitable exceptional sets implies that ff belongs to the Sobolev class Nloc1,p(X;Y){N}_{{\rm{loc}}}^{1,
Lahti Panu, Zhou Xiaodan
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Coupled fixed point results on metric spaces defined by binary operations

Karpatsʹkì Matematičnì Publìkacìï, 2018
In parallel with the various generalizations of the Banach fixed point theorem in metric spaces, this theory is also transported to some different types of spaces including ultra metric spaces, fuzzy metric spaces, uniform spaces, partial metric spaces, $
A. Karami, R. Shakeri, S. Sedghi, І. Altun   +3 more
doaj   +1 more source

Fixed Soft Points on Parametric Soft Metric Spaces

Journal of New Theory, 2022
This manuscript is devoted to investigating the existence of fixed soft points under conditions in the parametric soft metric spaces. Since the parametric soft metric spaces are the parametric expansions of the parametric metric and soft metric spaces ...
Yeşim Tunçay, Vildan Çetkin
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source