Results 251 to 260 of about 1,703,103 (308)

Compactly Generated Shape Index for Infinite-dimensional Local Dynamical Systems on Complete Metric Spaces

, 2018
Jintao Wang, Desheng Li, Jinqiao Duan
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Daily online adaptation enhances target coverage in prostate cancer radiotherapy: a retrospective analysis. [PDF]

Front Oncol
Malygina H, Salazar Zuniga B, Auerbach H, Ries M, Dzierma Y, Hecht M, Palm J.   +6 more
europepmc   +1 more source

The Coherence Density Law: C* as a Universal Solvency Constant for Systems, Minds, and Metrics

Beckingham, CD, Allan Christopher, Beckingham (SVM), Zen, Beckingham (LVM), Jarvis   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A Longitudinal Assessment of Greenhouse Gas Emissions From Inhaler Devices in a National Health System. [PDF]

JAMA
Weppner WG, Singh H, Boyd J, Smith G, Chesebro BB.   +4 more
europepmc   +1 more source

TESTING THE INFLUENCE OF COLLECTIVE EFFICACY BELIEFS ON GROUP LEVEL PERFORMANCE METRICS: AN INVESTIGATION OF THE VIRTUAL TEAM EFFICACY— PERFORMANCE RELATIONSHIP IN INFORMATION SYSTEMS PROJECT MANAGEMENT TEAMS

, 2005
Andrew Hardin
openalex   +1 more source

Effective Independence Metrics for Large Language Model Validator Ensembles: Application of Kish Design Effects to AI Hallucination Detection Systems

Joshua Beane
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Validating Physiologically-Based Pharmacokinetic Models Using the Continuous Ranked Probability Score: Beyond Being Correct on Average. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sluijterman L, van Borselen M, Greupink R, IntHout J.   +3 more
europepmc   +1 more source