Results 41 to 50 of about 40,958 (217)
Identifying 1-rectifiable measures in Carnot groups
Analysis and Geometry in Metric Spaces, 2023 We continue to develop a program in geometric measure theory that seeks to identify how measures in a space interact with canonical families of sets in the space. In particular, extending a theorem of M. Badger and R.
Badger Matthew, Li Sean, Zimmerman Scott
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FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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More stringy effects in target space from Double Field Theory
Journal of High Energy Physics, 2020 In Double Field Theory, the mass-squared of doubled fields associated with bosonic closed string states is proportional to N L + N R − 2. Massless states are therefore not only the graviton, anti-symmetric, and dilaton fields with (N L = 1, N R = 1) such
Chen-Te Ma, Franco Pezzella
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The "neutral" community structure of planktonic herbivores, tintinnid ciliates of the microzooplankton, across the SE Tropical Pacific Ocean [PDF]
Biogeosciences, 2007 We assessed the community characteristics of a group of planktonic herbivores across a species-rich area, the SE Pacific Ocean. A series of 22 stations between the Marquise Islands (7° S 142° W) and the coast of Chile (35° S 73° W) was ...
J. R. Dolan, M. E. Ritchie, J. Ras
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Natural Convection Heat Transfer from an Isothermal Plate
Thermo, 2023 Using boundary-layer theory, natural convection heat transfer formulas that are accurate over a wide range of Rayleigh numbers (Ra) were developed in the 1970s and 1980s for vertical and downward-facing plates.
Aubrey Jaffer
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
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The Performance of a Spectral Wave Model at Predicting Wave Farm Impacts
Energies, 2020 For renewable ocean wave energy to support global energy demands, wave energy converters (WECs) will likely be deployed in large numbers (farms), which will necessarily change the nearshore environment. Wave farm induced changes can be both helpful (e.g.,
J. Cameron McNatt +3 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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