Results 141 to 150 of about 981,969 (278)

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Observation Units: Definition, History, Data, Financial Considerations, and Metrics [PDF]

, 2014
Jason Napolitano, Inderpreet Saini
openalex   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

When bases clash: cultural, cognitive and practical ramifications of numeration systems used in parallel. [PDF]

Philos Trans R Soc Lond B Biol Sci
Bender A.
europepmc   +1 more source

A review of metrics of distribution with application to Conservation Units under Canada's Wild Salmon Policy

, 2011
Stephanie J. Peacock, Carrie A. Holt
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Relationships Among Commonly Used Measures of Cord Blood Potency, Aldhbr Cell Content, and Colony Forming Cell Content in Cord Blood Units Prior to Cryopreservation: Towards an Improved Metric for Potency of Banked Cord Blood [PDF]

, 2012
Kristin Page, Brigid Betz‐Stablein, Adam Mendizabal, S. Wease, Kevin Shoulars, Tracy Gentry, Andrew E. Balber, Joanne Kurtzberg   +7 more
openalex   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Causes and effects of fitness landscapes in system test generation: a replication study. [PDF]

Autom Softw Eng
Sahin O, Zhang M, Arcuri A.
europepmc   +1 more source

Unit Test Case Design Metrics in Test Driven Development

, 2012
Divya Prakash Shrivastava
openalex   +1 more source