Results 151 to 160 of about 981,969 (278)

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

V-RMS and Temperature metrics of the ball bearing units of an industrial blower

, 2023
Elisavet Karapalidou, Nikolaos Alexandris, Efstathios Antoniou, Stavros Vologiannidis, John Kalomiros, Dimitrios Varsamis   +5 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

A composite metric for evaluating system resilience with non-idealistic performance curves. [PDF]

PLoS One
Yeligeti M, Gils HC, Nowak W.
europepmc   +1 more source

Dual-Metric-Driven Thermal–Fluid Coupling Modeling and Thermal Management Optimization for High-Speed Electric Multiple Unit Electrical Cabinets [PDF]

Yaxuan Wang, Cuifeng Xu, Shou-Kang Chen, Z. Y. Deng, Zhaosheng Teng   +4 more
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

The Price Equation Reveals a Universal Force-Metric-Bias Law of Algorithmic Learning and Natural Selection. [PDF]

Entropy (Basel)
Frank SA.
europepmc   +1 more source

On the Geometry of Tangent Bundle and Unit Tangent Bundle with Deformed-Sasaki Metric

, 2023
Abderrahım Zagane
openalex   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Mimetic Metrics for the DGSEM. [PDF]

J Sci Comput
Bach D, Rueda-Ramírez A, Kopriva DA, Gassner GJ.   +3 more
europepmc   +1 more source