Results 341 to 350 of about 149,141 (380)
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JAMA: The Journal of the American Medical Association, 1982
To the Editor.— Although metronidazole is mutagenic in rats 1 and mice, 2 and is reported to alter DNA synthesis, 3 two previous human studies 4,5 have found no positive association between metronidazole use and cancer rates. In view of the limited amount of available human data, we report here on a follow-up study of some 12,000 users of ...
Hershel Jick +2 more
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To the Editor.— Although metronidazole is mutagenic in rats 1 and mice, 2 and is reported to alter DNA synthesis, 3 two previous human studies 4,5 have found no positive association between metronidazole use and cancer rates. In view of the limited amount of available human data, we report here on a follow-up study of some 12,000 users of ...
Hershel Jick +2 more
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Medical Clinics of North America, 1995
Metronidazole is a bactericidal antibiotic with strong activity against most anaerobes and certain parasites. The drug has excellent bioavailability and good penetration in most tissues, including the cerebrospinal fluid and brain abscess contents. It is usually well tolerated with few side effects.
Sherwood L. Gorbach, Matthew E. Falagas
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Metronidazole is a bactericidal antibiotic with strong activity against most anaerobes and certain parasites. The drug has excellent bioavailability and good penetration in most tissues, including the cerebrospinal fluid and brain abscess contents. It is usually well tolerated with few side effects.
Sherwood L. Gorbach, Matthew E. Falagas
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Metronidazole Hypersensitivity
Annals of Pharmacotherapy, 1994OBJECTIVE: To report a case of a possible hypersensitivity reaction induced by metronidazole. CASE SUMMARY: An Asian woman with a history of recurrent vaginitis had previously developed localized erythema while on intravaginal metronidazole and nystatin.
S, Knowles, T, Choudhury, N H, Shear
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The American Journal of Digestive Diseases, 1974
Previous reports indicate that metronidazole is highly effective in the therapy of colonic amebiasis and in the treatment of hepatic amebic abscesses when combined with aspiration. A retrospective review of 15 cases of intestinal amebiasis and 12 patients with amebic liver abscesses treated with metronidazole alone is reported.
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Previous reports indicate that metronidazole is highly effective in the therapy of colonic amebiasis and in the treatment of hepatic amebic abscesses when combined with aspiration. A retrospective review of 15 cases of intestinal amebiasis and 12 patients with amebic liver abscesses treated with metronidazole alone is reported.
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Neurotoxicity of Metronidazole
Annals of Internal Medicine, 1985Excerpt To the editor: In their review of antibiotic neurotoxicity, Snavely and Hodges (1) mention that the neurotoxicity of isoniazid stems largely from antagonism of vitamin B6.
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Drug Metabolism and Drug Interactions, 1992
The distribution of metronidazole following intravenous metronidazole (MTZ) and metronidazole phosphate disodium (MNP) in mice was investigated by HPLC. The results showed no significant differences in the metronidazole concentrations of liver, kidney, heart, spleen, fat, brain, lung, stomach, jejunum, skeletal muscle, ovary, testis and epididymis (P ...
Tun Li, Shouwei Qu
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The distribution of metronidazole following intravenous metronidazole (MTZ) and metronidazole phosphate disodium (MNP) in mice was investigated by HPLC. The results showed no significant differences in the metronidazole concentrations of liver, kidney, heart, spleen, fat, brain, lung, stomach, jejunum, skeletal muscle, ovary, testis and epididymis (P ...
Tun Li, Shouwei Qu
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Is metronidazole carcinogenic?
Mutation Research/Reviews in Mutation Research, 2002Metronidazole (MTZ, 1-[2-hydroxyethyl]-2-methyl-5-nitroimidazole), an antiparasitic and antibacterial compound, is one of the world's most used drugs. MTZ is potentially carcinogenic to humans due to the following facts: it is a proven mutagen in bacterial systems, it is genotoxic to human cells and also, it is carcinogenic to animals.
Andres Bendesky +2 more
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Metronidazole and Serum Lipids
Acta Clinica Belgica, 1985SCOPUS: ar.j ; info:eu-repo/semantics ...
Ducobu, Jean, Fontaine, Cécile
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Dalton Transactions, 2015
A series of water-soluble silver(i) complexes of the type [Ag(MTZ)2X] [MTZ = 1-(2-hydroxyethyl)-2-methyl-5-nitro-1H-imidazole (metronidazole drug); X = NO3(-), ClO4(-), CF3COO(-), BF4(-) and CH3SO3(-)] was synthesised by the reactions of various Ag(i ...
Urszula Kalinowska-Lis +6 more
semanticscholar +1 more source
A series of water-soluble silver(i) complexes of the type [Ag(MTZ)2X] [MTZ = 1-(2-hydroxyethyl)-2-methyl-5-nitro-1H-imidazole (metronidazole drug); X = NO3(-), ClO4(-), CF3COO(-), BF4(-) and CH3SO3(-)] was synthesised by the reactions of various Ag(i ...
Urszula Kalinowska-Lis +6 more
semanticscholar +1 more source
The use of metronidazole during pregnancy: a review of evidence.
Current Drug Safety, 2015OBJECTIVE To review the available evidence concerning the relationship between the exposure to metronidazole during pregnancy and the risk of preterm delivery and birth defects.
O. Sheehy +3 more
semanticscholar +1 more source