Results 21 to 30 of about 141,183 (240)

Theory building and technical innovations for spatial planning of China's metropolitan areas: insights from planning of Greater Shanghai Metropolitan Area

Frontiers of Urban and Rural Planning
Based on limited theoretical applicability of metropolitan area concept under China’s circumstances and the planning practice in Greater Shanghai Metropolitan Area, this article proposes a Chinese understanding on the concept of “Metropolitan Area ...
Jian Xiong, Juan Sun, Qiyu Tu, Liting Yan   +3 more
doaj   +1 more source

Les mobilisations sociales dans les territoires périphériques de Casablanca pendant les années 1990

L’Année du Maghreb, 2015
This article is a study of the forms, aims and organizational modes of mobilization of people living in the peripheral area of southern Casablanca in the 1990s.
Wafae Belarbi
doaj   +1 more source

Case report: Patient specific combination of surgery and immunotherapy in advanced squamous cell carcinoma of the head and neck – a case series and review of literature

Frontiers in Immunology, 2022
BackgroundPrognosis of patients with recurrent or metastatic head and neck cancer is generally poor. Adjuvant immunotherapy (IT) featuring immune checkpoint inhibition (ICI) is standard of care in advanced stage head and neck squamous cell carcinoma ...
Manuel Olmos, Manuel Olmos, Manuel Olmos, Rainer Lutz, Rainer Lutz, Rainer Lutz, Tjark-Ole Büntemeyer, Tjark-Ole Büntemeyer, Tjark-Ole Büntemeyer, Jacek Glajzer, Jacek Glajzer, Jacek Glajzer, Christopher-Philipp Nobis, Christopher-Philipp Nobis, Christopher-Philipp Nobis, Jutta Ries, Jutta Ries, Jutta Ries, Tobias Möst, Tobias Möst, Tobias Möst, Markus Eckstein, Markus Eckstein, Markus Hecht, Markus Hecht, Markus Hecht, Antoniu-Oreste Gostian, Antoniu-Oreste Gostian, Antoniu-Oreste Gostian, Michael Erdmann, Michael Erdmann, Michael Erdmann, Yannick Foerster, Yannick Foerster, Yannick Foerster, Marco Kesting, Marco Kesting, Marco Kesting, Manuel Weber, Manuel Weber, Manuel Weber   +40 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Mammographic density and prognosis in primary breast cancer patients

Breast, 2021
Purpose: Mammographic density (MD) is one of the strongest risk factors for breast cancer (BC). However, the influence of MD on the BC prognosis is unclear.
Felix Heindl, Peter A. Fasching, Alexander Hein, Carolin C. Hack, Katharina Heusinger, Paul Gass, Patrik Pöschke, Frederik A. Stübs, Rüdiger Schulz-Wendtland, Arndt Hartmann, Ramona Erber, Matthias W. Beckmann, Julia Meyer, Lothar Häberle, Sebastian M. Jud, Julius Emons   +15 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Conventional and three-dimensional photography as a tool to map distribution patterns of in-transit melanoma metastases on the lower extremity

Frontiers in Medicine, 2023
BackgroundIn melanoma, in-transit metastases characteristically occur at the lower extremity along lymphatic vessels.ObjectivesThe objective of this study was to evaluate conventional or three-dimensional photography as a tool to analyze in-transit ...
Kilian Müller, Carola Berking, Carola Berking, Caroline Voskens, Caroline Voskens, Markus V. Heppt, Markus V. Heppt, Lucie Heinzerling, Elias A. T. Koch, Elias A. T. Koch, Rafaela Kramer, Rafaela Kramer, Susanne Merkel, Susanne Merkel, Beatrice Schuler-Thurner, Beatrice Schuler-Thurner, Vera Schellerer, Theresa Steeb, Theresa Steeb, Anja Wessely, Anja Wessely, Michael Erdmann, Michael Erdmann   +22 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey, Jessica Fitzpatrick, Maria Dall'Era, Charmayne Dunlop‐Thomas, Courtney Hoge, S. Sam Lim, Patricia P. Katz, Jinoos Yazdany, Laura C. Plantinga   +8 more
wiley   +1 more source