Results 41 to 50 of about 2,630,297 (317)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Mexico’s Seguro Popular: Achievements and Challenges
In Mexico, Seguro Popular is a landmark government program aimed to guarantee universal access to health services, especially for the most vulnerable populations.
Antonio Chemor Ruiz +2 more
doaj +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
T he oldest representation of a physician in our country can be found at the Museo de Antropologia in Mexico City. It stands 9.5 cm tall and dates from 1500 BC. Little is known about surgery in our country before the appearance of the Mayan and Aztec cultures.
H, Orozco, M A, Mercado
openaire +2 more sources
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Throughout the world, tropical glaciers are rapidly receding and some are at risk of complete loss within the next several decades. It is therefore important to monitor these glacial regions to better understand the factors affecting glacier loss and ...
Donna Viola +2 more
doaj +1 more source
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni +7 more
wiley +1 more source
Gender-related beliefs and attitudes about tobacco use and smoking cessation in Mexico
Background. While overall trends in tobacco use among men are declining, tobacco use continues to rise significantly among women in developing countries.
Rosibel Rodríguez-Bolaños +6 more
doaj +1 more source
Disorder‐Broadened Topological Hall Phase and Anomalous Hall Scaling in FeGe
By systematically introducing defects into FeGe via ion‐beam modification, we demonstrate that disorder broadens the temperature regime over which the topological Hall effect ‐ a signature of skyrmions or other chiral textures — appears, while also increasing its magnitude.
Chaman Gupta +11 more
wiley +1 more source

