Results 71 to 80 of about 1,870 (159)

Suppressive Effects of Kouboku on Methyl Mercaptan Production and Biofilm Formation in Porphyromonas gingivalis

Molecular Oral Microbiology, Volume 40, Issue 3, Page 128-136, June 2025.
ABSTRACT Porphyromonas gingivalis, the bacterium responsible for periodontitis, produces several pathogenic factors, including methyl mercaptan, which contribute to the disease. Kouboku (Magnoliaceae), a Chinese herbal medicine, has been shown to suppress methyl mercaptan production from P. gingivalis.
Yuri Taniguchi, Kazuhisa Ouhara, Yoko Sato, Mikio Shoji, Yitong Hou, Ruoqi Zhai, Ryousuke Fujimori, Naoya Kuwahara, Tetsuya Tamura, Shinji Matsuda, Noriyoshi Mizuno   +10 more
wiley   +1 more source

Exploring Constrained Type-2 fuzzy sets [PDF]

, 2018
Fuzzy logic has been widely used to model human reasoning thanks to its inherent capability of handling uncertainty. In particular, the introduction of Type-2 fuzzy sets added the possibility of expressing uncertainty even on the definition of the ...
D'Alterio, P, Garibaldi, JM, Pourabdollah, A   +2 more
core   +2 more sources

Role of CRISPR‐Cas systems in periodontal disease pathogenesis and potential for periodontal therapy: A review

Molecular Oral Microbiology, Volume 40, Issue 1, Page 1-16, February 2025.
Abstract Clustered regularly interspaced short palindromic repeats (CRISPRs) are DNA sequences capable of editing a host genome sequence. CRISPR and its specific CRISPR‐associated (Cas) protein complexes have been adapted for various applications. These include activating or inhibiting specific genetic sequences or acting as molecular scissors to cut ...
Aditi Chopra, Geeta Bhuvanagiri, Kshitija Natu, Avneesh Chopra   +3 more
wiley   +1 more source

A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers. [PDF]

, 2016
Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known.
Bell, Sara N, Clotfelter, Sarah P, de Souza, Jorge ES, de Souza, Sandro J, Fonseca, André F, Kolodner, Richard D, Martinez, Sandra L, Nene, Rahul V, Putnam, Christopher D, Somach, Steven B, Srivatsan, Anjana   +10 more
core   +2 more sources

Metabolic Changes in Oral Fibroblasts After Exposure to Bacterial Extracellular Vesicles From Three Strains of Porphyromonas gingivalis

Cellular Microbiology, Volume 2025, Issue 1, 2025.
Aims Porphyromonas gingivalis is a keystone pathogen in periodontitis that releases bacterial extracellular vesicles (bEVs) with a content derived from the membrane and cytosol of the bacteria itself. The bEVs are taken up by host tissue cells, such as oral fibroblasts, yet their effects on human cells remain incompletely understood. Methods The aim of
Helene Rygvold Haugsten, Aleksandra Lipka, Anne Karin Kristoffersen, Morten Enersen, Anni Nieminen, Tine M. Søland, Trude M. Haug, Hilde Kanli Galtung, Suraiya Saleem   +8 more
wiley   +1 more source

Glycolanguage of the oral microbiota

Molecular Oral Microbiology, Volume 39, Issue 5, Page 291-320, October 2024.
Oral bacteria speak a sophisticated glycolanguage transmitted through versatile glycoinfrastructure, carbohydrate‐active enzymes, and lectins, which contributes decisively to their success in the oral habitat. Deciphering this glycolanguage opens new avenues for novel antibacterials to treat oral diseases. Abstract The oral cavity harbors a diverse and
Fiona F. Hager‐Mair, Susanne Bloch, Christina Schäffer   +2 more
wiley   +1 more source

Periodontal pathogens and cancer development

Periodontology 2000, Volume 96, Issue 1, Page 112-149, October 2024.
Abstract Increasing evidence suggests a significant association between periodontal disease and the occurrence of various cancers. The carcinogenic potential of several periodontal pathogens has been substantiated in vitro and in vivo. This review provides a comprehensive overview of the diverse mechanisms employed by different periodontal pathogens in
Yuxi Zhou, Joerg Meyle, Sabine Groeger
wiley   +1 more source

Charakterisierung von Interaktionspartnern der Homeodomänenproteine bE und bW und Untersuchungen zur chromatinvermittelten Regulation der pathogenen Differenzierung von Ustilago maydi [PDF]

, 2003
Der Erreger des Maisbeulenbrandes, der Basidiomycet Ustilago maydis, ist ein fakultativ biotropher Pilz, der in seiner saprophytischen Lebensphase in zwei distinkten Paarungstypen vorliegt, die sich in den a- und den b-Inkompatibilitätsloci unterscheiden.
Jamnischek, Alexander, Jamnischek, Alexander   +1 more
core   +1 more source

Polyamine oxidation enzymes regulate sexual mating/filamentation and pathogenicity in Sporisorium scitamineum

Molecular Plant Pathology, Volume 25, Issue 9, September 2024.
Polyamines homeostasis control dimorphic switch of sugarcane smut fungus via modulation of autophagy and intracellular reactive oxygen species levels. Abstract Sugarcane smut fungus Sporisorium scitamineum produces polyamines putrescine (PUT), spermidine (SPD), and spermine (SPM) to regulate sexual mating/filamentous growth critical for pathogenicity ...
Kai Yin, Zhijian Hu, Meiting Yuan, Weidong Chen, Xinping Bi, Guobing Cui, Zhibin Liang, Yi Zhen Deng   +7 more
wiley   +1 more source

Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. [PDF]

, 2013
Like ubiquitin, the small ubiquitin-related modifier (SUMO) proteins can form oligomeric chains, but the biological functions of these superstructures are not well understood. Here, we created mutant yeast strains unable to synthesize SUMO chains (smt3(
Andrews, Brenda J, Boone, Charles, Brown, Grant W, Costanzo, Michael, Giaever, Guri, Johnson, Erica S, Lewicki, Megan C, Nislow, Corey, Raught, Brian, Srikumar, Tharan, Tkach, Johnny M, Tsui, Kyle, van Bakel, Harm   +12 more
core   +2 more sources