Results 41 to 50 of about 98,345 (280)

Minkowski Functionals of Convergence Maps and the Lensing Figure of Merit

, 2019
Minkowski functionals (MFs) quantify the topological properties of a given field probing its departure from Gaussianity. We investigate their use on lensing convergence maps in order to see whether they can provide further insights on the underlying ...
Cardone, Vincenzo F., Er, Xinzhong, Maoli, Roberto, Scaramella, Roberto, Tereno, Ismael, Vicinanza, Martina   +5 more
core   +1 more source

Statistical and Systematic Errors in Measurement of Weak-Lensing Minkowski Functionals: Application to Canada-France-Hawaii Lensing Survey

, 2014
The measurement of cosmic shear using weak gravitational lensing is a challenging task that involves a number of complicated procedures. We study in detail the systematic errors in the measurement of weak lensing Minkowski Functionals (MFs). Specifically,
Shirasaki, Masato, Yoshida, Naoki
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Inflammation aggravates disease severity in Marfan syndrome patients. [PDF]

PLoS ONE, 2012
BACKGROUND: Marfan syndrome (MFS) is a pleiotropic genetic disorder with major features in cardiovascular, ocular and skeletal systems, associated with large clinical variability. Numerous studies reveal an involvement of TGF-β signaling.
Teodora Radonic, Piet de Witte, Maarten Groenink, Vivian de Waard, Rene Lutter, Marco van Eijk, Marnix Jansen, Janneke Timmermans, Marlies Kempers, Arthur J Scholte, Yvonne Hilhorst-Hofstee, Maarten P van den Berg, J Peter van Tintelen, Gerard Pals, Marieke J H Baars, Barbara J M Mulder, Aeilko H Zwinderman   +16 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effect of Mask Regions on Weak Lensing Statistics

, 2013
Sky masking is unavoidable in wide-field weak lensing observations. We study how masks affect the measurement of statistics of matter distribution probed by weak gravitational lensing.
Hamana, Takashi, Shirasaki, Masato, Yoshida, Naoki   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Microfiber ingestion in Patagonotothen kreffti from the Namuncurá/Burdwood Bank Marine Protected Area

Marine and Fishery Sciences
Microfibers (MFs) are an anthropogenic pollutant with a major impact on the marine environment. Due to their size, they can be ingested directly (from the environment) or indirectly (with their prey) by organisms. The aim of this study was to analyze and
Mariel Ojeda, Paula Bianconi, Guido N. Rimondino, Cintia P. Fraysse, Claudia C. Boy, Analía F. Pérez   +5 more
doaj   +1 more source

Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]

, 2013
Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di, Festuccia, Claudio, Gravina, Giovanni Luca, Mancini, Andrea, Marampon, Francesco, Pasquale, Boris Di, Ranieri, Guido, Ricevuto, Enrico   +7 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source