Results 51 to 60 of about 98,573 (277)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Dark Solitons with Majorana Fermions in Spin-Orbit-Coupled Fermi Gases

, 2014
We show that a single dark soliton can exist in a spin-orbit-coupled Fermi gas with a high spin imbalance, where spin-orbit coupling favors uniform superfluids over non-uniform Fulde-Ferrell-Larkin-Ovchinnikov states, leading to dark soliton excitations ...
Mao, Li, Wu, Biao, Xu, Yong, Zhang, Chuanwei   +3 more
core   +1 more source

Primordial Non-Gaussianity and Analytical Formula for Minkowski Functionals of the Cosmic Microwave Background and Large-scale Structure [PDF]

, 2006
We derive analytical formulae for the Minkowski Functions of the cosmic microwave background (CMB) and large-scale structure (LSS) from primordial non-Gaussianity.
Chiaki Hikage, Eiichiro Komatsu, Hikage C., Mecke K. R., Novikov D., Takahiko Matsubara   +5 more
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Nutritional Characterization of Whole Mangosteen Pulp with Seeds and Its Application as an Alternate Functional Ingredient in Crackers

Foods
Mangosteen (Garcinia mangostana L.) fruits are high in nutrients and phytochemical compounds. The use of fresh whole mangosteen fruit pulp, including the seeds (MFS), instead of flour and sugar in crackers not only enhances the functional nutritional and
Nisa Saelee, Roberto Castro-Muñoz, Worawan Panpipat, Manat Chaijan   +3 more
doaj   +1 more source

Association of thoracic spine deformity and cardiovascular disease in a mouse model for Marfan syndrome.

PLoS ONE, 2019
AIMS:Cardiovascular manifestations are a major cause of mortality in Marfan syndrome (MFS). Animal models that mimic the syndrome and its clinical variability are instrumental for understanding the genesis and risk factors for cardiovascular disease in ...
Rodrigo Barbosa de Souza, Luis Ernesto Farinha-Arcieri, Marcia Helena Braga Catroxo, Ana Maria Cristina Rebelo Pinto da Fonseca Martins, Roberto Carlos Tedesco, Luis Garcia Alonso, Ivan Hong Jun Koh, Lygia V Pereira   +7 more
doaj   +1 more source

Ventricular‐Vascular Coupling in Marfan and Non‐Marfan Aortopathies

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundMarfan syndrome (MFS) and familial non–syndromal thoracic aortic aneurysm and dissection (ns‐TAAD) are genetic aortopathies causing aortic dilatation with increased aortic stiffness.
Farina Loeper, Jantine Oosterhof, Mark van den Dorpel, Denise van der Linde, Yaxin Lu, Elizabeth Robertson, Brett Hambly, Richmond Jeremy   +7 more
doaj   +1 more source

A Pilot Study on Serial Nerve Ultrasound in Miller Fisher Syndrome

Frontiers in Neurology, 2020
Objective: Miller Fisher syndrome (MFS) is predominantly a clinical diagnosis, with classic triad of ophthalmoplegia, ataxia, and generalized reduced reflexes.
Hsueh-Wen Hsueh, Kai-Chieh Chang, Chi-Chao Chao, Sung-Tsang Hsieh, Sung-Tsang Hsieh   +4 more
doaj   +1 more source

Open cluster survival within the solar circle: Teutsch145 and Teutsch146 [PDF]

, 2009
Teutsch145 and Teutsch146 are shown to be open clusters (OCs) orbiting well inside the Solar circle, a region where several dynamical processes combine to disrupt most OCs on a time-scale of a few 10^8yrs.
B. Barbuy, Baumgardt, Bergond, Bica, Bica, Bica, Bica, Bonatto, Bonatto, Bonatto, Bonatto, Bonatto, Bonatto, Bonatto, Bonatto, Bonatto, C. Bonatto, Cardelli, Drimmel, E. Bica, Freudenreich, Friel, Geller, Ghez, Gieles, Girardi, Goodwin, Hole, Khalisi, King, Kronberger, Kroupa, Lamers, Lata, Maciejewski, Momany, O'Donnell, Oort, Ortolani, Piskunov, Russeil, S. Ortolani, Salpeter, Schlegel, Skrutskie, Spitzer, Trager, Trippe, Vallée, van den Bergh, van den Bergh, Vlajić, von Hoerner   +52 more
core   +2 more sources