Results 291 to 300 of about 556,334 (392)

The Biology and Underlying Mechanisms of Cross-Presentation of Exogenous Antigens on MHC-I Molecules.

Annual Review of Immunology, 2017
Freidrich M Cruz, Jeff D. Colbert, E. Merino, B. Kriegsman, K. Rock   +4 more
semanticscholar   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Two homologous sequences of Grp78 and HSP70 represent tumor antigens shared with streptococcal superantigens in eliciting an antitumor immune response: an immunoinformatic investigation. [PDF]

Front Immunol
Finotti P.
europepmc   +1 more source

Unfinished Business: Evolution of the MHC and the Adaptive Immune System of Jawed Vertebrates.

Annual Review of Immunology, 2018
J. Kaufman
semanticscholar   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

Annals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap, Ellen Morwitch, Samuel A. Tanner, Sarah M. Thomson, Alex Eisner, Rod A. Lea, Trevor J. Kilpatrick, Jeannette Lechner‐Scott, Rodney J. Scott, Alexandre Xavier, Vicki E. Maltby, Robyn M. Lucas, Bruce V. Taylor, Brett A. Lidbury, Simon A. Broadley, Ingrid van der Mei, Mehari Woldemariam Merid, Boris Novakovic, Richard Saffery, Anna Karin Hedström, Pernilla Stridh, Tomas Olsson, Maja Jagodic, Lars Alfredsson, Anne‐Louise Ponsonby, for the Ausimmune Investigator Group, Caron Chapman, Alan Coulthard, Keith Dear, Terry Dwyer, Trevor Kilpatrick, Robyn Lucas, Tony McMichael, Anne‐Louise Ponsonby, Bruce Taylor, Patricia Valery, Ingrid van der Mei, David Williams   +37 more
wiley   +1 more source

Decoding the prenatal clock of sheep muscle fiber type differentiation: a temporal map from embryonic to mature types. [PDF]

Front Cell Dev Biol
Gu Z, Duan W, Liu C, Li W, Zhang N, Han B, Liu M.   +6 more
europepmc   +1 more source

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei, Chunliu Huang, Zenghua Zhou, Yanni Lan   +3 more
wiley   +1 more source

Immunoinformatics-Based Multi-Epitope Vaccine Design Against <i>P. falciparum-</i>Causing Malaria: A Computational Approach. [PDF]

Health Sci Rep
Larbi AA, Mensah C, Korankye R, Darkwah AA, Agyemang EB, Ayikpah IY, Kwarteng A.   +6 more
europepmc   +1 more source

NLRC5/MHC class I transactivator is a target for immune evasion in cancer

Proceedings of the National Academy of Sciences of the United States of America, 2016
S. Yoshihama, J. Roszik, Isaac Downs, T. Meissner, Saptha Vijayan, B. Chapuy, Tabasum Sidiq, M. Shipp, G. Lizée, Koichi S. Kobayashi   +9 more
semanticscholar   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

Advanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos, Matteo Battaglini, Gianni Ciofani   +2 more
wiley   +1 more source