Results 311 to 320 of about 556,334 (392)

Tumor-specific major histocompatibility-II expression predicts pathological complete response to atezolizumab combined to chemotherapy in triple-negative breast cancer. [PDF]

NPJ Breast Cancer
Balko JM, Licata L, Wang XQ, Dugo M, Huang CS, Egle D, Bermejo B, Zamagni C, Thill M, Anton A, Russo S, Sevillano E, Ciruelos EM, Greil R, Semiglazov V, Colleoni M, Kelly CM, Mariani G, Del Mastro L, Zambelli S, Viale G, Callari M, Viale G, Pusztai L, Gianni L, Ali HR, Bianchini G.   +26 more
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Rheumatic Diseases

Arthritis &Rheumatology, EarlyView.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Computational Methods in Immunoinformatics: Epitope Discovery and Diagnostic Applications. [PDF]

ACS Omega
Bulla ACS, Sbano da Silva A, Prado Sereno B, Dias MFR, Leal da Silva M.   +4 more
europepmc   +1 more source

Rejection versus escape: the tumor MHC dilemma

Cancer Immunology and Immunotherapy, 2017
F. Garrido, F. Ruiz-Cabello, N. Aptsiauri   +2 more
semanticscholar   +1 more source

Orchestration of Skin Pathology in Cutaneous Lupus Erythematosus by HLA Class I Down‐Regulated Senescent Epidermal Basal Cells

Arthritis &Rheumatology, EarlyView.
Objective This study investigates the role of senescent epidermal basal cells in cutaneous lupus erythematosus (CLE) pathogenesis using skin samples from patients with CLE and a mouse model of systemic lupus erythematosus (SLE). Methods Cellular senescence profiling used datasets from the NCBI GEO database and Accelerating Medicines Partnership (AMP ...
Sena Yamamoto, Yuki Saito, Tsukasa Sato, Seina Nakano, Dain Kasseki, Ayaka Nagao, Norihiro Miura, Kentaro Nagaoka, Arisa Kita, Maki Miyajima, Shogo Ijima, Koji Taniguchi, Atsushi Niida, Takako S. Chikenji   +13 more
wiley   +1 more source

Stretch activation combats force loss from fatigue in fast-contracting mouse skeletal muscle fibers. [PDF]

J Gen Physiol
Woods PC, Swank DM, Miller MS.
europepmc   +1 more source

Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones

Arthritis &Rheumatology, EarlyView.
Objective Psoriatic arthritis (PsA) is an HLA class I–associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T cell phenotype and clonality.
Lucy E. Durham, Frances Humby, Nora Ng, Roman Laddach, Elizabeth H. Gray, Sarah E. Ryan, Kathryn J. A. Steel, Rosie Ross, Giovanni A. M. Povoleri, Rosamond Nuamah, Kathy Fung, Athul Menon Kallayil, Pawan Dhami, Bruce W. Kirkham, Leonie S. Taams   +14 more
wiley   +1 more source

Immunoregulatory properties of cell free DNA. [PDF]

Cell Mol Life Sci
Ferrera F, Altosole T, Tardito S, Astone G, Bernardi C, Parodi A, Marini C, Conteduca G, Cichero E, Salis A, Arpesella L, Camporesi L, Lagazio A, Rigo V, Pigozzo A, Damonte G, Fossa P, Fenoglio D, De Palma R, Inghirami G, Filaci G.   +20 more
europepmc   +1 more source

Comparative Effectiveness of Abatacept Versus Adalimumab in Shared Epitope Positive and Negative Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective The effect of the shared epitope (SE) and valine at position 11 (Val11) of HLA–DRB1 on the activation of CD4+ T cells is expected to be diminished by abatacept, a costimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting. We aimed to compare the difference in effectiveness
Chuan Fu Yap, Nisha Nair, Seema D. Sharma, John Bowes, Amirah Binti Mohammad Ariff, Ann W. Morgan, John D. Isaacs, Anthony G. Wilson, Kimme L. Hyrich, Suzan Verstappen, James Bluett, Andrew P. Morris, Anne Barton, Darren Plant, Sebastien Viatte   +14 more
wiley   +1 more source

Immunoevasion strategies for African swine fever virus: Modulation of antigen presentation pathways. [PDF]

Virulence
Lv P, Wang Z, Chen H, Chen Y, Liao H, Wei K, Lv S, Cui M.   +7 more
europepmc   +1 more source